%0 Journal Article %1 mahaffy:2000ly %A Mahaffy, R E %A Shih, C K %A MacKintosh, F C %A Käs, J %D 2000 %J Physical review letters %K 3T3 Atomic Cells,Acrylic Force,Microspheres,Polymers,Polymers: Mechanical,Viscosity Resins,Acrylic Resins: chemistry,Actins,Actins: chemistry,Animals,Biopolymers,Biopolymers: chemistry,Cells,Cells: chemistry,Elasticity,Mice,Microscopy, chemistry,Polystyrenes,Rheology,Rheology: methods,Stress, %N 4 %P 880--3 %T Scanning probe-based frequency-dependent microrheology of polymer gels and biological cells. %U http://www.ncbi.nlm.nih.gov/pubmed/10991422 %V 85 %X A new scanning probe-based microrheology approach is used to quantify the frequency-dependent viscoelastic behavior of both fibroblast cells and polymer gels. The scanning probe shape was modified using polystyrene beads for a defined surface area nondestructively deforming the sample. An extended Hertz model is introduced to measure the frequency-dependent storage and loss moduli even for thin cell samples. Control measurements of the polyacrylamide gels compare well with conventional rheological data. The cells show a viscoelastic signature similar to in vitro actin gels.

@article{mahaffy:2000ly, abstract = {A new scanning probe-based microrheology approach is used to quantify the frequency-dependent viscoelastic behavior of both fibroblast cells and polymer gels. The scanning probe shape was modified using polystyrene beads for a defined surface area nondestructively deforming the sample. An extended Hertz model is introduced to measure the frequency-dependent storage and loss moduli even for thin cell samples. Control measurements of the polyacrylamide gels compare well with conventional rheological data. The cells show a viscoelastic signature similar to in vitro actin gels.}, added-at = {2013-11-08T00:45:00.000+0100}, author = {Mahaffy, R E and Shih, C K and MacKintosh, F C and K{\"a}s, J}, bdsk-file-1 = {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}, bdsk-url-1 = {http://www.ncbi.nlm.nih.gov/pubmed/10991422}, biburl = {https://www.bibsonomy.org/bibtex/2342ef77dd0f43355988598e917ec0f88/andresgm}, date-modified = {2011-07-22 23:02:14 +0000}, interhash = {f845105b01debfa05d5a358ca1d2078f}, intrahash = {342ef77dd0f43355988598e917ec0f88}, issn = {0031-9007}, journal = {Physical review letters}, keywords = {3T3 Atomic Cells,Acrylic Force,Microspheres,Polymers,Polymers: Mechanical,Viscosity Resins,Acrylic Resins: chemistry,Actins,Actins: chemistry,Animals,Biopolymers,Biopolymers: chemistry,Cells,Cells: chemistry,Elasticity,Mice,Microscopy, chemistry,Polystyrenes,Rheology,Rheology: methods,Stress,}, month = jul, number = 4, pages = {880--3}, pmid = {10991422}, timestamp = {2013-11-08T00:45:00.000+0100}, title = {Scanning probe-based frequency-dependent microrheology of polymer gels and biological cells.}, url = {http://www.ncbi.nlm.nih.gov/pubmed/10991422}, volume = 85, year = 2000 }