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Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors

, , , и . J Biol Chem, 265 (6): 3202-11 (февраля 1990)Lohse, M J Benovic, J L Caron, M G Lefkowitz, R J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1990 Feb 25;265(6):3202-11..

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Building a new conceptual framework for receptor heteromers, , , , , , , , , и 8 other автор(ы). Nat Chem Biol, 5 (3): 131-4 (марта 2009)Ferre, Sergi Baler, Ruben Bouvier, Michel Caron, Marc G Devi, Lakshmi A Durroux, Thierry Fuxe, Kjell George, Susan R Javitch, Jonathan A Lohse, Martin J Mackie, Ken Milligan, Graeme Pfleger, Kevin D G Pin, Jean-Philippe Volkow, Nora D Waldhoer, Maria Woods, Amina S Franco, Rafael Research Support, N.I.H., Extramural United States Nature chemical biology Nat Chem Biol. 2009 Mar;5(3):131-4..The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor, , , , , и . Nature, 335 (6188): 358-60 (сентября 1988)Fargin, A Raymond, J R Lohse, M J Kobilka, B K Caron, M G Lefkowitz, R J Research Support, Non-U.S. Gov't England Nature Nature. 1988 Sep 22;335(6188):358-60..Mechanisms involved in adrenergic receptor desensitization, , , , , и . Biochem Soc Trans, 18 (4): 541-4 (августа 1990)Collins, S Bouvier, M Lohse, M J Benovic, J L Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. Review England Biochemical Society transactions Biochem Soc Trans. 1990 Aug;18(4):541-4..Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor, , , , , и . Symp Soc Exp Biol, (1990)Hausdorff, W P Lohse, M J Bouvier, M Liggett, S B Caron, M G Lefkowitz, R J 1F32GM13182/GM/NIGMS NIH HHS/United States HL02386/HL/NHLBI NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Symposia of the Society for Experimental Biology Symp Soc Exp Biol. 1990;44:225-40..Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems, , , , , , , и . J Biol Chem, 267 (12): 8558-64 (апреля 1992)Lohse, M J Andexinger, S Pitcher, J Trukawinski, S Codina, J Faure, J P Caron, M G Lefkowitz, R J DK 19318/DK/NIDDK NIH HHS/United States HL 16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1992 Apr 25;267(12):8558-64..beta-Arrestin: a protein that regulates beta-adrenergic receptor function, , , , и . Science, 248 (4962): 1547-50 (июня 1990)Lohse, M J Benovic, J L Codina, J Caron, M G Lefkowitz, R J DK19318/DK/NIDDK NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states Science (New York, N.Y.) Science. 1990 Jun 22;248(4962):1547-50..Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-125I iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe, , , , , , и . Mol Pharmacol, 36 (1): 15-21 (июля 1989)Raymond, J R Fargin, A Lohse, M J Regan, J W Senogles, S E Lefkowitz, R J Caron, M G HL-16037/HL/NHLBI NIH HHS/United States NS-19576/NS/NINDS NIH HHS/United States S07-RR-05405/RR/NCRR NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states Molecular pharmacology Mol Pharmacol. 1989 Jul;36(1):15-21..Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms, , , , и . Biochemistry, 31 (12): 3193-7 (марта 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;31(12):3193-7..Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model, , , , и . Vitam Horm, (1991)Collins, S Lohse, M J O'Dowd, B Caron, M G Lefkowitz, R J Review United states Vitamins and hormones Vitam Horm. 1991;46:1-39..Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase, , , , , , и . Br J Clin Pharmacol, (1990)Benovic, J L Onorato, J Lohse, M J Dohlman, H G Staniszewski, C Caron, M G Lefkowitz, R J England British journal of clinical pharmacology Br J Clin Pharmacol. 1990;30 Suppl 1:3S-12S..