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Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

S. Ramus, A. Antoniou, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, L. McGuffog, O. Sinilnikova, S. Healey, D. Barrowdale, A. Lee, M. Thomassen, A. Gerdes, T. Kruse, U. Jensen, A. Skytte, M. Caligo, A. Liljegren, A. Lindblom, H. Olsson, U. Kristoffersson, M. Stenmark-Askmalm, B. Melin, S. Domchek, K. Nathanson, T. Rebbeck, A. Jakubowska, J. Lubinski, K. Jaworska, K. Durda, E. Złowocka, J. Gronwald, T. Huzarski, T. Byrski, C. Cybulski, A. Toloczko-Grabarek, A. Osorio, J. Benitez, M. Duran, M. Tejada, U. Hamann, M. Rookus, van Leeuwen, Flora E, C. Aalfs, Meijers-Heijboer, Hanne E J, van Asperen, Christi J, van Roozendaal, K E P, N. Hoogerbrugge, J. Collée, M. Kriege, van der Luijt, Rob B, S. Peock, D. Frost, S. Ellis, R. Platte, E. Fineberg, D. Evans, F. Lalloo, C. Jacobs, R. Eeles, J. Adlard, R. Davidson, D. Eccles, T. Cole, J. Cook, J. Paterson, F. Douglas, C. Brewer, S. Hodgson, P. Morrison, L. Walker, M. Porteous, M. Kennedy, H. Pathak, A. Godwin, D. Stoppa-Lyonnet, V. Caux-Moncoutier, A. Pauw, M. Gauthier-Villars, S. Mazoyer, M. Léoné, A. Calender, C. Lasset, V. Bonadona, A. Hardouin, P. Berthet, Y. Bignon, N. Uhrhammer, L. Faivre, C. Loustalot, S. Buys, M. Daly, A. Miron, M. Terry, W. Chung, E. John, M. Southey, D. Goldgar, C. Singer, M. Tea, G. Pfeiler, A. Fink-Retter, Hansen, Thomas V O, B. Ejlertsen, O. Johannsson, K. Offit, T. Kirchhoff, M. Gaudet, J. Vijai, M. Robson, M. Piedmonte, K. Phillips, L. van Le, J. Hoffman, A. Ewart Toland, M. Montagna, S. Tognazzo, E. Imyanitov, C. Issacs, R. Janavicius, C. Lazaro, I. Blanco, E. Tornero, M. Navarro, K. Moysich, B. Karlan, J. Gross, E. Olah, T. Vaszko, S. Teo, P. Ganz, M. Beattie, C. Dorfling, van Rensburg, Elizabeth J, O. Diez, A. Kwong, R. Schmutzler, B. Wappenschmidt, C. Engel, A. Meindl, N. Ditsch, N. Arnold, S. Heidemann, D. Niederacher, S. Preisler-Adams, D. Gadzicki, R. Varon-Mateeva, H. Deissler, A. Gehrig, C. Sutter, K. Kast, B. Fiebig, D. Schäfer, T. Caldes, de la Hoya, Miguel, H. Nevanlinna, K. Aittomäki, M. Plante, A. Spurdle, S. Neuhausen, Y. Ding, X. Wang, N. Lindor, Z. Fredericksen, V. Pankratz, P. Peterlongo, S. Manoukian, B. Peissel, D. Zaffaroni, B. Bonanni, L. Bernard, R. Dolcetti, L. Papi, L. Ottini, P. Radice, M. Greene, P. Mai, I. Andrulis, G. Glendon, H. Ozcelik, Pharoah, Paul D P, S. Gayther, J. Simard, D. Easton, F. Couch, и G. Chenevix-Trench. Human mutation, 33 (4): 690–702 (2012)

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Fergus J King

Robert Fergus

Kiri Couchman

Solveig Coucheron-Aamot

Richard Allen Couch

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Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriersD. Cox, J. Simard, D. Sinnett, Y. Hamdi, P. Soucy, M. Ouimet, L. Barjhoux, C. Verny-Pierre, L. McGuffog, S. Healey и 99 other автор(ы). Human molecular genetics, 20 (23): 4732–4747 (2011)Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriersL. Walker, Z. Fredericksen, X. Wang, R. Tarrell, V. Pankratz, N. Lindor, J. Beesley, S. Healey, X. Chen, D. Stoppa-Lyonnet и 63 other автор(ы). Breast cancer research : BCR, 12 (6): R102 (2010)A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activityL. Guidugli, V. Pankratz, N. Singh, J. Thompson, C. Erding, C. Engel, R. Schmutzler, S. Domchek, K. Nathanson, P. Radice и 5 other автор(ы). Cancer research, 73 (1): 265–275 (2013)Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancersJ. French, M. Ghoussaini, S. Edwards, K. Meyer, K. Michailidou, S. Ahmed, S. Khan, M. Maranian, M. O'Reilly, K. Hillman и 201 other автор(ы). American journal of human genetics, 92 (4): 489–503 (2013)Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)N. Mavaddat, D. Barrowdale, I. Andrulis, S. Domchek, D. Eccles, H. Nevanlinna, S. Ramus, A. Spurdle, M. Robson, M. Sherman и 123 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 (1): 134–147 (2012)Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriersF. Couch, M. Gaudet, A. Antoniou, S. Ramus, K. Kuchenbaecker, P. Soucy, J. Beesley, X. Chen, X. Wang, T. Kirchhoff и 180 other автор(ы). Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 (4): 645–657 (2012)Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerS. Bojesen, K. Pooley, S. Johnatty, J. Beesley, K. Michailidou, J. Tyrer, S. Edwards, H. Pickett, H. Shen, C. Smart и 427 other автор(ы). Nature genetics, 45 (4): 371-84, 384e1-2 (2013)No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort studyT. Rebbeck, A. Antoniou, T. Llopis, H. Nevanlinna, K. Aittomäki, J. Simard, A. Spurdle, F. Couch, Pereira, Lutecia H Mateus, M. Greene и 34 other автор(ы). Breast cancer research and treatment, 115 (1): 185–192 (2009)Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriersA. Antoniou, A. Spurdle, O. Sinilnikova, S. Healey, K. Pooley, R. Schmutzler, B. Versmold, C. Engel, A. Meindl, N. Arnold и 76 other автор(ы). American journal of human genetics, 82 (4): 937–948 (2008)Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskF. Couch, X. Wang, L. McGuffog, A. Lee, C. Olswold, K. Kuchenbaecker, P. Soucy, Z. Fredericksen, D. Barrowdale, J. Dennis и 252 other автор(ы). PLoS genetics, 9 (3): e1003212 (2013)

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