cchar, v. 1.6: Count characters in sequence data.
cpg, v. 0.7: Compute the CpG content of DNA sequences.
cutSeq, v. 0.11: Cut regions from molecular sequences.
generateQuerySbjct, v. 0.4: Generate pairs of homologous DNA sequences.
gd, v. 0.12: Calculate genetic diversity (pi, S, and Tajima's D) from aligned DNA sequences with or without sliding window.
getSeq, v. 0.4: Get specific sequences from a FASTA file containing multiple entries.
ms2dna, v. 1.16: Generate samples of homologous DNA sequences evolved under defined evolutionary scenarios by converting the output of Richard Hudson's coalescent simulation program ms. As of version 1.11, it can also deal with output generated by Gary Chen's fast coalescent simulator MaCS using the pipeline macs [options] | msformatter | ms2dna -a.
randomizeSeq, v. 0.8: Randomize sequences.
sequencer, v. 1.14: Simulate shotgun sequencing with paired (as of version 1.11) or unpaired reads and a user-defined error rate.
simK, v. 0.4: Simulate pair of sequences with given number of substitutions/site (K).
In 2007, the National Center for Genome Resources (NCGR) in Santa Fe, New Mexico, best known for the development of bioinformatics tools, established the Schizophrenia Genome Project. Taking Illumina GA sequence data, NCGR scientists used a combination of homegrown Alpheus software and JMP Genomics (from SAS) to develop a streamlined workflow for the acquisition, analysis, and management of huge amounts of next-generation sequencing data—in this case, mRNA.
The G-language Genome Analysis Environment is a generic genome analysis environment aiming to: 1. Construct an integrated environment for the development of analysis software. 2. Systematically accumulate existing analysis software methodologies for
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