LMOND is a program specifically developed for generating and handling alignment independent descriptors called GRIND (GRid INdependent Descriptors). These are a new generation of 3D-molecular descriptors with application in 3D-QSAR, QSAR, virtual screenin
F. Archetti, S. Lanzeni, E. Messina, and L. Vanneschi. Genetic Programming and Evolvable Machines, 8 (4):
413--432(December 2007)special issue on medical applications of Genetic and
Evolutionary Computation.