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Anticancer Effects of a Plant Lignan 7-Hydroxymatairesinol on a Prostate Cancer Model In Vivo -- Bylund et al. 230 (3): 217 -- Experimental Biology and Medicine

http://www.ebmonline.org/cgi/content/full/230/3/217

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Lignans inhibit androgen-metabolizing enzymes, affect bioavailability of androgens by reducing sex hormone–binding globulin/dihydrotestosterone binding, thus accelerating metabolic clearance of endogenous androgens.

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