Artificial intelligence (AI) has enormous potential to improve the safety of healthcare, from increasing diagnostic accuracy,1 to optimising treatment planning,2 to forecasting outcomes of care.3 However, integrating AI technologies into the delivery of healthcare is likely to introduce a range of new risks and amplify existing ones. For instance, failures in widely used software have the potential to quickly affect large numbers of patients4; hidden assumptions in underlying data and models can lead to AI systems delivering dangerous recommendations that are insensitive to local care processes,5 6 and opaque AI techniques such as deep learning can make explaining and learning from failure extremely difficult.7 8 To maximise the benefits of AI in healthcare and to build trust among patients and practitioners, it will therefore be essential to robustly govern the risks that AI poses to patient safety.. To read the full article, log in using your NHS OpenAthens details.