Experimental and Clinical Psychopharmacology (Sep 27, 2018). DOI:10.1037/pha0000225 Prescription opioid misuse among chronic pain patients is undergirded by self-regulatory deficits, affective distress, and opioid-cue reactivity. Dispositional mindfulness has been associated with enhanced self-regulation, lower distress, and adaptive autonomic responses following drug-cue exposure. We hypothesized that dispositional mindfulness might serve as a protective factor among opioid-treated chronic pain patients.. To read the full article, log in using your NHS OpenAthens details.