cchar, v. 1.6: Count characters in sequence data.
cpg, v. 0.7: Compute the CpG content of DNA sequences.
cutSeq, v. 0.11: Cut regions from molecular sequences.
generateQuerySbjct, v. 0.4: Generate pairs of homologous DNA sequences.
gd, v. 0.12: Calculate genetic diversity (pi, S, and Tajima's D) from aligned DNA sequences with or without sliding window.
getSeq, v. 0.4: Get specific sequences from a FASTA file containing multiple entries.
ms2dna, v. 1.16: Generate samples of homologous DNA sequences evolved under defined evolutionary scenarios by converting the output of Richard Hudson's coalescent simulation program ms. As of version 1.11, it can also deal with output generated by Gary Chen's fast coalescent simulator MaCS using the pipeline macs [options] | msformatter | ms2dna -a.
randomizeSeq, v. 0.8: Randomize sequences.
sequencer, v. 1.14: Simulate shotgun sequencing with paired (as of version 1.11) or unpaired reads and a user-defined error rate.
simK, v. 0.4: Simulate pair of sequences with given number of substitutions/site (K).
?. J. Virol., 81 (15):
8211-8224(2007)"HCV replicates as a quasispecies rather than as a clonal population. (...) The average amino acid difference between the consensus sequence and the individual quasispecies variants was 1.8%, which was smaller than the average distance between the quasispecies variants themselves (2.3%). Phylogenetic analyses revealed that the consensus sequence was either in the center or near the base of the phylogenetic tree for each HCV gene.".
M. Aguade, N. Miyashita, и C. Langley. Genetics, 122 (3):
607-615(июля 1989)"In particular, the low genetic diversity seen in regions of low recombination in Drosophila and other organisms (Aguade et al. 1989; Aquadro et al. 1994) must be due to some kind of selection.".