%0 Journal Article %1 Matsuda2000 %A Matsuda, Y. %A Kouno, S. %A Hiroyama, Y. %A Kuraya, K. %A Kamitomo, M. %A Ibara, S. %A Hatae, M. %D 2000 %J Eur J Obstet Gynecol Reprod Biol %K Abruptio Placentae; Adolescent; Adult; Birth Weight; Case-Control Studies; Cerebral Palsy; Female; Fetal Membranes, Premature Rupture; Gestational Age; Heart Rate, Fetal; Humans; Logistic Models; Magnesium Sulfate; Maternal Pregnancy; Pregnancy Complications, Infectious; Pregnancy, High-Risk; Risk Factors; Uterine Diseases %N 2 %P 159--164 %T Intrauterine infection, magnesium sulfate exposure and cerebral palsy in infants born between 26 and 30 weeks of gestation. %V 91 %X OBJECTIVE: To identify prenatal events associated with cerebral palsy (CP) in infants born between 26 and 30 weeks of gestation. STUDY DESIGN: Case (n=22)-control (n=170) study was performed using a logistic regression model. RESULTS: Significant association of intrauterine infection with increased risk of CP was found in a logistic regression model that controlled for abnormal FHR patterns, placental infection, fetal acidosis at birth (umbilical artery pH<7. 1), and low Apgar score (<7) (odds ratio (OR) 5.47, 95\% confidence interval (CI) 1.46-20.4). Magnesium sulfate exposure was associated with decreased risk (OR 0.13, CI 0.03-0.66) after exclusion of premature rupture of the membranes and abruptio placentae. In the magnesium exposure group, cases were infants born less than 28 weeks of gestation (3/21 vs. 0/61, P=0.015). CONCLUSION: In this case-control study, both intrauterine infection and magnesium sulfate exposure were significant factors related to the occurrence of cerebral palsy.

@article{Matsuda2000, abstract = {OBJECTIVE: To identify prenatal events associated with cerebral palsy (CP) in infants born between 26 and 30 weeks of gestation. STUDY DESIGN: Case (n=22)-control (n=170) study was performed using a logistic regression model. RESULTS: Significant association of intrauterine infection with increased risk of CP was found in a logistic regression model that controlled for abnormal FHR patterns, placental infection, fetal acidosis at birth (umbilical artery pH<7. 1), and low Apgar score (<7) (odds ratio (OR) 5.47, 95\% confidence interval (CI) 1.46-20.4). Magnesium sulfate exposure was associated with decreased risk (OR 0.13, CI 0.03-0.66) after exclusion of premature rupture of the membranes and abruptio placentae. In the magnesium exposure group, cases were infants born less than 28 weeks of gestation (3/21 vs. 0/61, P=0.015). CONCLUSION: In this case-control study, both intrauterine infection and magnesium sulfate exposure were significant factors related to the occurrence of cerebral palsy.}, added-at = {2014-07-19T20:46:04.000+0200}, author = {Matsuda, Y. and Kouno, S. and Hiroyama, Y. and Kuraya, K. and Kamitomo, M. and Ibara, S. and Hatae, M.}, biburl = {https://www.bibsonomy.org/bibtex/2b799b22a918607fd190c982b948feef7/ar0berts}, groups = {public}, interhash = {018654a06a236cb5d0f302516d97d55d}, intrahash = {b799b22a918607fd190c982b948feef7}, journal = {Eur J Obstet Gynecol Reprod Biol}, keywords = {Abruptio Placentae; Adolescent; Adult; Birth Weight; Case-Control Studies; Cerebral Palsy; Female; Fetal Membranes, Premature Rupture; Gestational Age; Heart Rate, Fetal; Humans; Logistic Models; Magnesium Sulfate; Maternal Pregnancy; Pregnancy Complications, Infectious; Pregnancy, High-Risk; Risk Factors; Uterine Diseases}, month = Aug, number = 2, pages = {159--164}, pii = {S0301211599002560}, pmid = {10869789}, timestamp = {2014-07-19T20:46:04.000+0200}, title = {Intrauterine infection, magnesium sulfate exposure and cerebral palsy in infants born between 26 and 30 weeks of gestation.}, username = {ar0berts}, volume = 91, year = 2000 }