%0 Journal Article %1 ianniravn2023exploring %A Ianni-Ravn, Mariadaria K %A Petr, Martin %A Racimo, Fernando %D 2023 %I Cold Spring Harbor Laboratory %J bioRxiv %K dispersal_kernel spatial_statistics tree_sequence %R 10.1101/2023.03.27.534388 %T Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences %U https://www.biorxiv.org/content/early/2023/03/30/2023.03.27.534388 %X Space is a fundamental dimension of evolutionary change, determining how individuals disperse and interact with each other. Consequently, space has an important influence on the structure of genealogies and the distribution of genetic variants over time. Recently, the development of highly flexible simulation tools and computational methods for genealogical inference has greatly increased the potential for incorporating space into models of population genetic variation. It is now possible to explore how spatial ecological parameters can influence the distribution of genetic variation among individuals with unprecedented detail. In this study, we explore the effects of three specific parameters (the dispersal distance, competition distance and mate choice distance) on the spatial structure of genealogies relating individuals across a genome. We carry out a series of in silico experiments using forwards-in-time simulations, to determine how these parameters influence the distance between closely- and distantly-related individuals in these genealogies. We also assess the accuracy of the maximum likelihood estimation of the dispersal distance in a Gaussian model of dispersal from tree-sequence data. Our results showcase the potential for linking phylogeography, population genetics and ecology, in order to answer fundamental questions about the nature of spatial interactions across a landscape.Competing Interest StatementThe authors have declared no competing interest.

@article{ianniravn2023exploring, abstract = {Space is a fundamental dimension of evolutionary change, determining how individuals disperse and interact with each other. Consequently, space has an important influence on the structure of genealogies and the distribution of genetic variants over time. Recently, the development of highly flexible simulation tools and computational methods for genealogical inference has greatly increased the potential for incorporating space into models of population genetic variation. It is now possible to explore how spatial ecological parameters can influence the distribution of genetic variation among individuals with unprecedented detail. In this study, we explore the effects of three specific parameters (the dispersal distance, competition distance and mate choice distance) on the spatial structure of genealogies relating individuals across a genome. We carry out a series of in silico experiments using forwards-in-time simulations, to determine how these parameters influence the distance between closely- and distantly-related individuals in these genealogies. We also assess the accuracy of the maximum likelihood estimation of the dispersal distance in a Gaussian model of dispersal from tree-sequence data. Our results showcase the potential for linking phylogeography, population genetics and ecology, in order to answer fundamental questions about the nature of spatial interactions across a landscape.Competing Interest StatementThe authors have declared no competing interest.}, added-at = {2023-03-31T05:52:42.000+0200}, author = {Ianni-Ravn, Mariadaria K and Petr, Martin and Racimo, Fernando}, biburl = {https://www.bibsonomy.org/bibtex/2ae5db5adccffa650076593481e3589be/peter.ralph}, doi = {10.1101/2023.03.27.534388}, elocation-id = {2023.03.27.534388}, eprint = {https://www.biorxiv.org/content/early/2023/03/30/2023.03.27.534388.full.pdf}, interhash = {1e4418486afb8b96232e67deaa5badf5}, intrahash = {ae5db5adccffa650076593481e3589be}, journal = {bioRxiv}, keywords = {dispersal_kernel spatial_statistics tree_sequence}, publisher = {Cold Spring Harbor Laboratory}, timestamp = {2023-03-31T05:52:42.000+0200}, title = {Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences}, url = {https://www.biorxiv.org/content/early/2023/03/30/2023.03.27.534388}, year = 2023 }