The authors develop a new method to mine genomic cancer data to uncover complex indels. These simultaneous deletions and insertions have been over-looked by previous sequencing data analysis methods, and the Pindel-C algorithm uncovers new information about their potential contribution to tumorigenesis.
Description
Systematic discovery of complex insertions and deletions in human cancers | Nature Medicine
%0 Journal Article
%1 ye2016systematic
%A Ye, Kai
%A Wang, Jiayin
%A Jayasinghe, Reyka
%A Lameijer, Eric-Wubbo
%A McMichael, Joshua F
%A Ning, Jie
%A McLellan, Michael D
%A Xie, Mingchao
%A Cao, Song
%A Yellapantula, Venkata
%A Huang, Kuan-lin
%A Scott, Adam
%A Foltz, Steven
%A Niu, Beifang
%A Johnson, Kimberly J
%A Moed, Matthijs
%A Slagboom, P Eline
%A Chen, Feng
%A Wendl, Michael C
%A Ding, Li
%D 2016
%J Nature Medicine
%K cancer-research fulltext indel shouldread software variant-calling whole-genome-sequencing
%N 1
%P 97--104
%R 10.1038/nm.4002
%T Systematic discovery of complex insertions and deletions in human cancers
%U https://doi.org/10.1038/nm.4002
%V 22
%X The authors develop a new method to mine genomic cancer data to uncover complex indels. These simultaneous deletions and insertions have been over-looked by previous sequencing data analysis methods, and the Pindel-C algorithm uncovers new information about their potential contribution to tumorigenesis.
@article{ye2016systematic,
abstract = {The authors develop a new method to mine genomic cancer data to uncover complex indels. These simultaneous deletions and insertions have been over-looked by previous sequencing data analysis methods, and the Pindel-C algorithm uncovers new information about their potential contribution to tumorigenesis.},
added-at = {2020-09-10T00:34:51.000+0200},
author = {Ye, Kai and Wang, Jiayin and Jayasinghe, Reyka and Lameijer, Eric-Wubbo and McMichael, Joshua F and Ning, Jie and McLellan, Michael D and Xie, Mingchao and Cao, Song and Yellapantula, Venkata and Huang, Kuan-lin and Scott, Adam and Foltz, Steven and Niu, Beifang and Johnson, Kimberly J and Moed, Matthijs and Slagboom, P Eline and Chen, Feng and Wendl, Michael C and Ding, Li},
biburl = {https://www.bibsonomy.org/bibtex/2742ca88894cba8e7315ba07a5aad4e11/marcsaric},
description = {Systematic discovery of complex insertions and deletions in human cancers | Nature Medicine},
doi = {10.1038/nm.4002},
interhash = {36adc62dd54821fb5795fc2bac57b094},
intrahash = {742ca88894cba8e7315ba07a5aad4e11},
issn = {1546170X},
journal = {Nature Medicine},
keywords = {cancer-research fulltext indel shouldread software variant-calling whole-genome-sequencing},
number = 1,
pages = {97--104},
refid = {Ye2016},
timestamp = {2020-09-10T00:34:51.000+0200},
title = {Systematic discovery of complex insertions and deletions in human cancers},
url = {https://doi.org/10.1038/nm.4002},
volume = 22,
year = 2016
}