%0 Journal Article %1 Munyombwe_2019 %A Munyombwe, Theresa %A Hall, Marlous %A Dondo, Tatendashe Bernadette %A Alabas, Oras A %A Gerard, Oliver %A West, Robert M %A Pujades-Rodriguez, Mar %A Hall, Alistair %A Gale, Chris P %D 2019 %I BMJ %J Heart %K mi&qol %N 1 %P 33--39 %R 10.1136/heartjnl-2019-315510 %T Quality of life trajectories in survivors of acute myocardial infarction: a national longitudinal study %U https://doi.org/10.1136%2Fheartjnl-2019-315510 %V 106 %X Aim: To define trajectories of perceived health-related quality of life (HRQoL) among survivors of acute myocardial infarction (AMI) and identify factors associated with trajectories. Methods: Data on HRQoL among 9566 survivors of AMI were collected from 77 National Health Service hospitals in England between 1 November 2011 and 24 June 2015. Longitudinal HRQoL was collected using the EuroQol five-dimension questionnaire measured at hospitalisation, 1, 6 and 12 months post-AMI. Trajectories of perceived HRQoL post-MI were determined using multilevel regression analysis and latent class growth analysis (LCGA). Results: One or more percieved health problems in mobility, self-care, usual activities, pain/discomfort and anxiety/depression was reported by 69.1% (6607/9566) at hospitalisation and 59.7% (3011/5047) at 12 months. Reduced HRQoL was associated with women (-4.07, 95% CI -4.88 to -3.25), diabetes (-2.87, 95% CI -3.87 to -1.88), previous AMI (-1.60, 95% CI -2.72 to -0.48), previous angina (-1.72, 95% CI -2.77 to -0.67), chronic renal failure (-2.96, 95% CI -5.08 to -0.84; -3.10, 95% CI -5.72 to -0.49), chronic obstructive pulmonary disease (-3.89, 95% CI -5.07 to -2.72) and cerebrovascular disease (-2.60, 95% CI -4.24 to -0.96). LCGA identified three subgroups of HRQoL which we labelled: improvers (68.1%), non-improvers (22.1%) and dis-improvers (9.8%). Non-improvers and dis-improvers were more likely to be women, non-ST-elevation myocardial infarction (NSTEMI) and have long-term health conditions, compared with improvers. Conclusions: Quality of life improves for the majority of survivors of AMI but is significantly worse and more likely to decline for women, NSTEMI and those with long-term health conditions. Assessing HRQoL both in hospital and postdischarge may be important in determining which patients could benefit from tailored interventions.

@article{Munyombwe_2019, abstract = {Aim: To define trajectories of perceived health-related quality of life (HRQoL) among survivors of acute myocardial infarction (AMI) and identify factors associated with trajectories. Methods: Data on HRQoL among 9566 survivors of AMI were collected from 77 National Health Service hospitals in England between 1 November 2011 and 24 June 2015. Longitudinal HRQoL was collected using the EuroQol five-dimension questionnaire measured at hospitalisation, 1, 6 and 12 months post-AMI. Trajectories of perceived HRQoL post-MI were determined using multilevel regression analysis and latent class growth analysis (LCGA). Results: One or more percieved health problems in mobility, self-care, usual activities, pain/discomfort and anxiety/depression was reported by 69.1% (6607/9566) at hospitalisation and 59.7% (3011/5047) at 12 months. Reduced HRQoL was associated with women (-4.07, 95% CI -4.88 to -3.25), diabetes (-2.87, 95% CI -3.87 to -1.88), previous AMI (-1.60, 95% CI -2.72 to -0.48), previous angina (-1.72, 95% CI -2.77 to -0.67), chronic renal failure (-2.96, 95% CI -5.08 to -0.84; -3.10, 95% CI -5.72 to -0.49), chronic obstructive pulmonary disease (-3.89, 95% CI -5.07 to -2.72) and cerebrovascular disease (-2.60, 95% CI -4.24 to -0.96). LCGA identified three subgroups of HRQoL which we labelled: improvers (68.1%), non-improvers (22.1%) and dis-improvers (9.8%). Non-improvers and dis-improvers were more likely to be women, non-ST-elevation myocardial infarction (NSTEMI) and have long-term health conditions, compared with improvers. Conclusions: Quality of life improves for the majority of survivors of AMI but is significantly worse and more likely to decline for women, NSTEMI and those with long-term health conditions. Assessing HRQoL both in hospital and postdischarge may be important in determining which patients could benefit from tailored interventions.}, added-at = {2020-11-03T05:04:10.000+0100}, author = {Munyombwe, Theresa and Hall, Marlous and Dondo, Tatendashe Bernadette and Alabas, Oras A and Gerard, Oliver and West, Robert M and Pujades-Rodriguez, Mar and Hall, Alistair and Gale, Chris P}, biburl = {https://www.bibsonomy.org/bibtex/26786d4aaae173118e4670605811994eb/rodrigogopar}, description = {Quality of life trajectories in survivors of acute myocardial infarction: a national longitudinal study | Heart}, doi = {10.1136/heartjnl-2019-315510}, interhash = {386d367cef416832b8a9ded676894e9e}, intrahash = {6786d4aaae173118e4670605811994eb}, journal = {Heart}, keywords = {mi&qol}, month = nov, number = 1, pages = {33--39}, publisher = {{BMJ}}, timestamp = {2020-11-03T05:04:10.000+0100}, title = {Quality of life trajectories in survivors of acute myocardial infarction: a national longitudinal study}, url = {https://doi.org/10.1136%2Fheartjnl-2019-315510}, volume = 106, year = 2019 }