Article,

Biogenic Zirconium Nanoparticles Synthesized from Silybum marianum: A Potent Antibacterial Agent Against Gingivitis bacteria

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (5): 1066-1076 (September 2023)

Abstract

The present paper incorporates the preparation of Zirconium Dioxide Nanoparticles (ZrO2NPs) through the green synthesis using extracts from the leaves of the wild Silybium marianum plant growing in Anbar regions. The plant has special compounds that can help reduce and stabilize nanoparticles. This can also make the nanoparticles less harmful. So, the nanoparticles have been characterized utilizing: Atomic Force Microscopy (AFM), Fourier Transform Infrared Spectroscopy (FT-IR), Ultraviolet-Visible Spectroscopy, Scanning Electron Microscopy (SEM) in conjunction with Energy Dispersive Spectroscopy (EDS) analysis as well as X-Ray Diffraction (XRD). According to the analysis conducted with the X-Ray Diffraction SEM, it was observed that the nano-zirconium particles possessed a round shape and were estimated to be around 55 in dimension.91 nanometers. The ZrO2NPs were used as antibacterial agents against bacteria that cause gum inflammation. In order to determine the levels of nano-zirconium, different quantities were tested at concentrations of 200, 250, and 300 µg/ml. The concentration of 250 µg/ml showed the highest diameter of inhibition against the behavior of the isolated bacteria P.mirabilis, S.mitis. Conversely, the lowest inhibitory diameter was at the concentration of 200 µg/ml. The study demonstrated the ability of ZrO2NPs in inhibiting the activity of bacteria causing gum inflammation.

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