%0 Journal Article %1 slatkin1998hitchhiking %A Slatkin, M %A Wiehe, T %D 1998 %J Genet Res %K hitchhiking low_migration spatial_structure %N 2 %P 155-160 %T Genetic hitch-hiking in a subdivided population %U http://www.ncbi.nlm.nih.gov/pubmed/9717437 %V 71 %X The problem of genetic hitch-hiking in a geographically subdivided population is analysed under the assumption that migration rates among populations are relatively small compared with the selection coefficient for a newly arising advantageous allele. The approximate method used in the paper is valid when the number of emigrants per generation (Nm) is less than one. The approximate analysis shows that hitch-hiking can result in substantial differences among populations in the frequencies of neutral alleles closely linked to the advantageous allele. Thus, in cases for which genetic hitch-hiking is thought to be responsible for low levels of genetic variability in regions of the genome with restricted crossing over, it might be possible to find confirmatory evidence for that hypothesis by finding unusual patterns of geographic differentiation in the same regions of the genome.

@article{slatkin1998hitchhiking, abstract = {The problem of genetic hitch-hiking in a geographically subdivided population is analysed under the assumption that migration rates among populations are relatively small compared with the selection coefficient for a newly arising advantageous allele. The approximate method used in the paper is valid when the number of emigrants per generation (Nm) is less than one. The approximate analysis shows that hitch-hiking can result in substantial differences among populations in the frequencies of neutral alleles closely linked to the advantageous allele. Thus, in cases for which genetic hitch-hiking is thought to be responsible for low levels of genetic variability in regions of the genome with restricted crossing over, it might be possible to find confirmatory evidence for that hypothesis by finding unusual patterns of geographic differentiation in the same regions of the genome.}, added-at = {2010-03-28T01:14:40.000+0100}, author = {Slatkin, M and Wiehe, T}, biburl = {https://www.bibsonomy.org/bibtex/27aaec2c16ca05c43660c298580b29a80/peter.ralph}, description = {Genetic hitch-hiking in a subdivided population. [Genet Res. 1998] - PubMed result}, interhash = {60c1a9d6c58909956a961756eb4039a4}, intrahash = {7aaec2c16ca05c43660c298580b29a80}, journal = {Genet Res}, keywords = {hitchhiking low_migration spatial_structure}, month = apr, number = 2, pages = {155-160}, pmid = {9717437}, timestamp = {2010-03-28T01:14:40.000+0100}, title = {Genetic hitch-hiking in a subdivided population}, url = {http://www.ncbi.nlm.nih.gov/pubmed/9717437}, volume = 71, year = 1998 }