Article,

The stepping stone model. II. Genealogies and the infinite sites model

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Ann. Appl. Probab., 15 (1B): 671--699 (2005)
DOI: 10.1214/105051604000000701

Abstract

This paper extends earlier work by Cox and Durrett, who studied the coalescence times for two lineages in the stepping stone model on the two-dimensional torus. We show that the genealogy of a sample of size n is given by a time change of Kingman’s coalescent. With DNA sequence data in mind, we investigate mutation patterns under the infinite sites model, which assumes that each mutation occurs at a new site. Our results suggest that the spatial structure of the human population contributes to the haplotype structure and a slower than expected decay of genetic correlation with distance revealed by recent studies of the human genome.

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