Abstract
Submandibular gland is rich source of epidermal growth factor (EGF). To investigate the role of salivary EGF on the development of male reproductive system we have performed the sialoadenectomy (removal of submandibular glands) of the 20 days old male mice and this sialoadenectomised mice was sacrificed on 45, 60 and
90th day. The testis, seminal vesicle, prostate gland, caput and cauda epididymis were dissected out for protein estimation and histological studies. It was found that the there was significant loss in the weight of these organs, protein content in the sialoadenectomised mice as compared to control. The histological structures of these organs were also changed in the sialoadenectomised mice.
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