%0 Journal Article %1 venkateswararaossudhiraa2013efficacy %A Venkateswara Rao. S, Sudhira. A, Kamakshamma. J %D 2013 %E and Fabricio Moraes de Almeida, %J SCIENCE PARK %K Chionanthus Diabetes Ethyl Glyco acetate extract proteins streptozotocin zeylanica %N 1 %T Efficacy Of Chionanthus Zeylanica L. Bark Extract On Blood Glucose, Plasma Insulin And Tissue Glycoproteins In Streptozotocin Induced Diabetic Rats %U http://www.scienceparks.in/ArticlePDF/6.pdf %V 1 %X The present study evaluated the anti-hyperglycemic activity of the Ethyl acetateextract of Chionanthus zeylanica bark on blood glucose, Plasma insulin and glycoprotein contents of albino rats. CZEt was administered at doses of 150, 300 and 450 mg/kg body weight respectively on streptozotocin induced diabetic rats for 2 weeks. The aim of this study was to investigate the effect of Ethyl acetate extract of Chionanthus zeylanica (CZEt) in streptozotocin induced diabetic, which was induced in male albino rats by a single intraperitoneal injection of streptozotocin (55 mg/kg). After injection, the animals were divided into five groups viz., control group, streptozotocin treated diabetic group, diabetic + CZEt (150,300,450 mg/kg) groups treated for 15 days. The study shows a significant increase in the levels of blood glucose, and plasma glycoproteins, while plasma insulin levels were significantly decreased in diabetic rats. There was also a significant decrease in the level of sialic acid and elevated levels of hexose, hexosamine in the liver and kidney of diabetic rats. Thus the study indicates that Chionanthus zeylanica L. possesses a significant beneficial effect on glycoprotein’s in addition to its antidiabetic action.

@article{venkateswararaossudhiraa2013efficacy, abstract = {The present study evaluated the anti-hyperglycemic activity of the Ethyl acetateextract of Chionanthus zeylanica bark on blood glucose, Plasma insulin and glycoprotein contents of albino rats. CZEt was administered at doses of 150, 300 and 450 mg/kg body weight respectively on streptozotocin induced diabetic rats for 2 weeks. The aim of this study was to investigate the effect of Ethyl acetate extract of Chionanthus zeylanica (CZEt) in streptozotocin induced diabetic, which was induced in male albino rats by a single intraperitoneal injection of streptozotocin (55 mg/kg). After injection, the animals were divided into five groups viz., control group, streptozotocin treated diabetic group, diabetic + CZEt (150,300,450 mg/kg) groups treated for 15 days. The study shows a significant increase in the levels of blood glucose, and plasma glycoproteins, while plasma insulin levels were significantly decreased in diabetic rats. There was also a significant decrease in the level of sialic acid and elevated levels of hexose, hexosamine in the liver and kidney of diabetic rats. Thus the study indicates that Chionanthus zeylanica L. possesses a significant beneficial effect on glycoprotein’s in addition to its antidiabetic action.}, added-at = {2014-08-15T10:59:45.000+0200}, author = {{Venkateswara Rao. S, Sudhira. A}, Kamakshamma. J}, biburl = {https://www.bibsonomy.org/bibtex/2d2f75c92c24205b7b4ddc6bf1b137020/sciencejournal}, editor = {and Fabricio Moraes de Almeida}, interhash = {d404f3f5997a7f44f7d1abd0b1df0bd5}, intrahash = {d2f75c92c24205b7b4ddc6bf1b137020}, journal = { SCIENCE PARK}, keywords = {Chionanthus Diabetes Ethyl Glyco acetate extract proteins streptozotocin zeylanica}, month = {July}, number = 1, timestamp = {2014-08-15T10:59:45.000+0200}, title = {Efficacy Of Chionanthus Zeylanica L. Bark Extract On Blood Glucose, Plasma Insulin And Tissue Glycoproteins In Streptozotocin Induced Diabetic Rats }, url = {http://www.scienceparks.in/ArticlePDF/6.pdf}, volume = 1, year = 2013 }