Article,

The cost of natural selection

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Journal of Genetics, 55 (3): 511 (Dec 1, 1957)
DOI: 10.1007/BF02984069

Abstract

Unless selection is very intense, the number of deaths needed to secure the substitution, by natural selection, of one gene for another at a locus, is independent of the intensity of selection. It is often about 30 times the number of organisms in a generation. It is suggested that, in horotelic evolution, the mean time taken for each gene substitution is . about 300 generations. This accords with the observed slowness of evolution.

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