The aim of this study was to develop the Mayo Dysphagia Questionnaire-30
Day (MDQ-30), a tool to measure esophageal dysphagia, by adapting
items from validated instruments for use in clinical trials, and
assess its feasibility, reproducibility, and concurrent validity.
Outpatients referred to endoscopy for dysphagia or seen in a specialty
clinic were recruited. Feasibility testing was done to identify problematic
items. Reproducibility was measured by test-retest format. Concurrent
validity reflects agreement between information gathered in a structured
interview versus the patients' written responses. The MDQ-30, a 28-item
instrument, took 10 min (range = 5-30 min) to complete. Four hundred
thirty-one outpatients 210 (49%) men; mean age = 61 years participated.
Overall, most concurrent validity kappa values for dysphagia were
very good to excellent with a median of 0.78 (min 0.28, max 0.95).
The majority of reproducibility kappa values for dysphagia were moderate
to excellent with a median kappa value of 0.66 (min 0.07, max 1.0).
Overall, concurrent validity and reproducibility kappa values for
gastroesophageal reflux disease (GERD) symptoms were 0.81 (95% CI
= 0.72, 0.91) and 0.66 (95% CI = 0.55, 0.77), respectively. Individual
item percent agreement was generally very good to excellent. Internal
consistency was excellent. We conclude that the MDQ-30 is an easy-to-complete
tool to evaluate reliably dysphagia symptoms over the last 30 days.
%0 Journal Article
%1 McElhiney2009
%A McElhiney, J.
%A Lohse, M. R.
%A Arora, A. S.
%A Peloquin, J. M.
%A Geno, D. M.
%A Kuntz, M. M.
%A Enders, F. B.
%A Fredericksen, M.
%A Abdalla, A. A.
%A Khan, Y.
%A Talley, N. J.
%A Diehl, N. N.
%A Beebe, T. J.
%A Harris, A. M.
%A Farrugia, G.
%A Graner, D. E.
%A Murray, J. A.
%A 3rd Locke,
%A Grothe, R. M.
%A Crowell, M. D.
%A Francis, D. L.
%A Grudell, A. M.
%A Dabade, T.
%A Ramirez, A.
%A Alkhatib, M.
%A Alexander, J. A.
%A Kimber, J.
%A Prasad, G.
%A Zinsmeister, A. R.
%A Romero, Y.
%D 2009
%J Dysphagia
%K imported
%T The Mayo Dysphagia Questionnaire-30: Documentation of Reliability
and Validity of a Tool for Interventional Trials in Adults with Esophageal
Disease
%U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19856027
%X The aim of this study was to develop the Mayo Dysphagia Questionnaire-30
Day (MDQ-30), a tool to measure esophageal dysphagia, by adapting
items from validated instruments for use in clinical trials, and
assess its feasibility, reproducibility, and concurrent validity.
Outpatients referred to endoscopy for dysphagia or seen in a specialty
clinic were recruited. Feasibility testing was done to identify problematic
items. Reproducibility was measured by test-retest format. Concurrent
validity reflects agreement between information gathered in a structured
interview versus the patients' written responses. The MDQ-30, a 28-item
instrument, took 10 min (range = 5-30 min) to complete. Four hundred
thirty-one outpatients 210 (49%) men; mean age = 61 years participated.
Overall, most concurrent validity kappa values for dysphagia were
very good to excellent with a median of 0.78 (min 0.28, max 0.95).
The majority of reproducibility kappa values for dysphagia were moderate
to excellent with a median kappa value of 0.66 (min 0.07, max 1.0).
Overall, concurrent validity and reproducibility kappa values for
gastroesophageal reflux disease (GERD) symptoms were 0.81 (95% CI
= 0.72, 0.91) and 0.66 (95% CI = 0.55, 0.77), respectively. Individual
item percent agreement was generally very good to excellent. Internal
consistency was excellent. We conclude that the MDQ-30 is an easy-to-complete
tool to evaluate reliably dysphagia symptoms over the last 30 days.
@article{McElhiney2009,
abstract = {The aim of this study was to develop the Mayo Dysphagia Questionnaire-30
Day (MDQ-30), a tool to measure esophageal dysphagia, by adapting
items from validated instruments for use in clinical trials, and
assess its feasibility, reproducibility, and concurrent validity.
Outpatients referred to endoscopy for dysphagia or seen in a specialty
clinic were recruited. Feasibility testing was done to identify problematic
items. Reproducibility was measured by test-retest format. Concurrent
validity reflects agreement between information gathered in a structured
interview versus the patients' written responses. The MDQ-30, a 28-item
instrument, took 10 min (range = 5-30 min) to complete. Four hundred
thirty-one outpatients [210 (49%) men; mean age = 61 years] participated.
Overall, most concurrent validity kappa values for dysphagia were
very good to excellent with a median of 0.78 (min 0.28, max 0.95).
The majority of reproducibility kappa values for dysphagia were moderate
to excellent with a median kappa value of 0.66 (min 0.07, max 1.0).
Overall, concurrent validity and reproducibility kappa values for
gastroesophageal reflux disease (GERD) symptoms were 0.81 (95% CI
= 0.72, 0.91) and 0.66 (95% CI = 0.55, 0.77), respectively. Individual
item percent agreement was generally very good to excellent. Internal
consistency was excellent. We conclude that the MDQ-30 is an easy-to-complete
tool to evaluate reliably dysphagia symptoms over the last 30 days.},
added-at = {2010-12-14T18:12:02.000+0100},
author = {McElhiney, J. and Lohse, M. R. and Arora, A. S. and Peloquin, J. M. and Geno, D. M. and Kuntz, M. M. and Enders, F. B. and Fredericksen, M. and Abdalla, A. A. and Khan, Y. and Talley, N. J. and Diehl, N. N. and Beebe, T. J. and Harris, A. M. and Farrugia, G. and Graner, D. E. and Murray, J. A. and 3rd Locke and Grothe, R. M. and Crowell, M. D. and Francis, D. L. and Grudell, A. M. and Dabade, T. and Ramirez, A. and Alkhatib, M. and Alexander, J. A. and Kimber, J. and Prasad, G. and Zinsmeister, A. R. and Romero, Y.},
biburl = {https://www.bibsonomy.org/bibtex/224a0da39d7433d16a2122c9427a2ab30/pharmawuerz},
endnotereftype = {Journal Article},
interhash = {0ab332aa784e98282e81c74d8520f203},
intrahash = {24a0da39d7433d16a2122c9427a2ab30},
issn = {1432-0460 (Electronic) 1432-0460 (Linking)},
journal = {Dysphagia},
keywords = {imported},
month = {Oct 24},
note = {Journal article Dysphagia Dysphagia. 2009 Oct 24.},
shorttitle = {The Mayo Dysphagia Questionnaire-30: Documentation of Reliability
and Validity of a Tool for Interventional Trials in Adults with Esophageal
Disease},
timestamp = {2010-12-14T18:12:25.000+0100},
title = {The Mayo Dysphagia Questionnaire-30: Documentation of Reliability
and Validity of a Tool for Interventional Trials in Adults with Esophageal
Disease},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19856027},
year = 2009
}