Neisseria meningitidis is a commensal bacterium of the human nasopharynx that occasionally provokes invasive disease. Carriage strains of N. meningitidis are heterogeneous, more frequent in nature and are transmitted among carriers. Disease is not a part of this transmission cycle and is caused by virulent strains. N. meningitidis is highly variable and variants that are modified in their virulence and/or transmissibility are continually generated. These events probably occur frequently, thus explaining not only the heterogeneous nature of meningococcal populations in carriers but probably also the evolutionary success of this human-restricted bacterium.
%0 Journal Article
%1 taha_duality_2002
%A Taha, Muhamed-Kheir
%A Deghmane, Ala-Eddine
%A Antignac, Aude
%A Zarantonelli, Maria Leticia
%A Larribe, Mireille
%A Alonso, Jean-Michel
%D 2002
%J Trends in Microbiology
%K Carrier Genetic Humans, Infections, Meningococcal Nasopharynx, Neisseria State, Variation, Virulence meningitidis,
%N 8
%P 376--82
%T The duality of virulence and transmissibility in Neisseria meningitidis
%U http://www.ncbi.nlm.nih.gov/pubmed/12160636
%V 10
%X Neisseria meningitidis is a commensal bacterium of the human nasopharynx that occasionally provokes invasive disease. Carriage strains of N. meningitidis are heterogeneous, more frequent in nature and are transmitted among carriers. Disease is not a part of this transmission cycle and is caused by virulent strains. N. meningitidis is highly variable and variants that are modified in their virulence and/or transmissibility are continually generated. These events probably occur frequently, thus explaining not only the heterogeneous nature of meningococcal populations in carriers but probably also the evolutionary success of this human-restricted bacterium.
@article{taha_duality_2002,
abstract = {Neisseria meningitidis is a commensal bacterium of the human nasopharynx that occasionally provokes invasive disease. Carriage strains of N. meningitidis are heterogeneous, more frequent in nature and are transmitted among carriers. Disease is not a part of this transmission cycle and is caused by virulent strains. N. meningitidis is highly variable and variants that are modified in their virulence and/or transmissibility are continually generated. These events probably occur frequently, thus explaining not only the heterogeneous nature of meningococcal populations in carriers but probably also the evolutionary success of this human-restricted bacterium.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Taha, {Muhamed-Kheir} and Deghmane, {Ala-Eddine} and Antignac, Aude and Zarantonelli, Maria Leticia and Larribe, Mireille and Alonso, {Jean-Michel}},
biburl = {https://www.bibsonomy.org/bibtex/226b065c96de57af88f35fbe485358b28/jelias},
interhash = {71ec9a1adc3d3bee6dc1f81d49957dbc},
intrahash = {26b065c96de57af88f35fbe485358b28},
issn = {{0966-842X}},
journal = {Trends in Microbiology},
keywords = {Carrier Genetic Humans, Infections, Meningococcal Nasopharynx, Neisseria State, Variation, Virulence meningitidis,},
month = aug,
note = {{PMID:} 12160636},
number = 8,
pages = {376--82},
timestamp = {2011-03-11T10:05:44.000+0100},
title = {The duality of virulence and transmissibility in Neisseria meningitidis},
url = {http://www.ncbi.nlm.nih.gov/pubmed/12160636},
volume = 10,
year = 2002
}