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Simulations of semiflexible networks: nonaffine deformations and nonlinear elastic response

Abstract Book of the XXIII IUPAP International Conference on Statistical Physics, 2007.
Authors: E. Conti and D.K. Danova and F.C. Mackintosh
Editors: Luciano Pietronero and Vittorio Loreto and Stefano Zapperi
URL: http://st23.statphys23.org/webservices/abstract/preview_pop.php?ID_PAPER=1074
Tags: actin biopolymer cytoskeleton elasticity networks nonlinear polymer semiflexible statphys23 topic-10
Abstract: The cytoskeleton of eukaryotic cells has several important functions such as mechanical stability, force sensing, intracellular transport and locomotion. The elasticity of the cytoskeleton is mainly due to a filamentous network of semiflexible polymers that includes both actin and microtubules. Such filaments are qualitatively different from flexible polymers because of their bending rigidity. This results in, among other things, strongly nonlinear elasticity of cytoskeletal networks. Such systems have recently been shown to exhibit negative normal stresses. We simulate model 2D networks of semiflexible filaments using both finite element and energy minimization techniques, in order to study the origins of such anomalous normal stress behavior. In particular, we examine the connection between normal stresses and nonaffine or heterogeneous strain of these networks.
| URL | BibTeX  
@incollection{statphys23_1074,
title = {Simulations of semiflexible networks: nonaffine deformations and nonlinear elastic response},
address = {Genova, Italy},
author = {E. Conti and D.K. Danova and F.C. Mackintosh},
booktitle = {Abstract Book of the XXIII IUPAP International Conference on Statistical Physics},
editor = {Luciano Pietronero and Vittorio Loreto and Stefano Zapperi},
month = {9-13 July},
url = {http://st23.statphys23.org/webservices/abstract/preview_pop.php?ID_PAPER=1074},
year = {2007},
abstract = {The cytoskeleton of eukaryotic cells has several important functions such as mechanical stability, force sensing, intracellular transport and locomotion. The elasticity of the cytoskeleton is mainly due to a filamentous network of semiflexible polymers that includes both actin and microtubules. Such filaments are qualitatively different from flexible polymers because of their bending rigidity. This results in, among other things, strongly nonlinear elasticity of cytoskeletal networks. Such systems have recently been shown to exhibit negative normal stresses. We simulate model 2D networks of semiflexible filaments using both finite element and energy minimization techniques, in order to study the origins of such anomalous normal stress behavior. In particular, we examine the connection between normal stresses and nonaffine or heterogeneous strain of these networks.},
keywords = {actin biopolymer cytoskeleton elasticity networks nonlinear polymer semiflexible statphys23 topic-10 }
}