The experimental parameters critical for the implementation of multidimensional solid-state NMR experiments that incorporate heteronuclear spin exchange at the magic angle are discussed. This family of experiments is exemplified by the three-dimensional experiment that correlates the (1)H chemical shift, (1)H-(15)N dipolar coupling, and (15)N chemical shift frequencies. The broadening effects of the homonuclear (1)H-(1)H dipolar couplings are suppressed using flip-flop (phase- and frequency-switched) Lee-Goldburg irradiations in both the (1)H chemical shift and the (1)H-(15)N dipolar coupling dimensions. The experiments are illustrated using the (1)H and (15)N chemical shift and dipolar couplings in a single crystal of (15)N-acetylleucine.
%0 Journal Article
%1 ramamoorthy_experimental_1999
%A Ramamoorthy, A
%A Wu, C H
%A Opella, S J
%D 1999
%J J. Magn. Reson.
%K Biomolecular,Hydrogen Bonding,Leucine,Nitrogen Isotopes,Nuclear Magnetic Resonance
%N 1
%P 131--140
%R 10.1006/jmre.1999.1827
%T Experimental aspects of multidimensional solid-state \NMR\ correlation spectroscopy
%V 140
%X The experimental parameters critical for the implementation of multidimensional solid-state NMR experiments that incorporate heteronuclear spin exchange at the magic angle are discussed. This family of experiments is exemplified by the three-dimensional experiment that correlates the (1)H chemical shift, (1)H-(15)N dipolar coupling, and (15)N chemical shift frequencies. The broadening effects of the homonuclear (1)H-(1)H dipolar couplings are suppressed using flip-flop (phase- and frequency-switched) Lee-Goldburg irradiations in both the (1)H chemical shift and the (1)H-(15)N dipolar coupling dimensions. The experiments are illustrated using the (1)H and (15)N chemical shift and dipolar couplings in a single crystal of (15)N-acetylleucine.
@article{ramamoorthy_experimental_1999,
abstract = {The experimental parameters critical for the implementation of multidimensional solid-state NMR experiments that incorporate heteronuclear spin exchange at the magic angle are discussed. This family of experiments is exemplified by the three-dimensional experiment that correlates the (1)H chemical shift, (1)H-(15)N dipolar coupling, and (15)N chemical shift frequencies. The broadening effects of the homonuclear (1)H-(1)H dipolar couplings are suppressed using flip-flop (phase- and frequency-switched) Lee-Goldburg irradiations in both the (1)H chemical shift and the (1)H-(15)N dipolar coupling dimensions. The experiments are illustrated using the (1)H and (15)N chemical shift and dipolar couplings in a single crystal of (15)N-acetylleucine.},
added-at = {2017-03-14T02:48:56.000+0100},
author = {Ramamoorthy, A and Wu, C H and Opella, S J},
biburl = {https://www.bibsonomy.org/bibtex/2373da4d6e5b386580f2f83770afaca23/nmrresource},
doi = {10.1006/jmre.1999.1827},
interhash = {7f5196e3f8802bc6448479fac3d2e36d},
intrahash = {373da4d6e5b386580f2f83770afaca23},
issn = {1090-7807},
journal = {J. Magn. Reson.},
keywords = {Biomolecular,Hydrogen Bonding,Leucine,Nitrogen Isotopes,Nuclear Magnetic Resonance},
month = sep,
number = 1,
pages = {131--140},
pmid = {10479555},
timestamp = {2017-03-14T02:49:21.000+0100},
title = {{Experimental aspects of multidimensional solid-state {\{}NMR{\}} correlation spectroscopy}},
volume = 140,
year = 1999
}