The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org
%0 Journal Article
%1 Morris:2014:Bioinformatics:24336642
%A Morris, T J
%A Butcher, L M
%A Feber, A
%A Teschendorff, A E
%A Chakravarthy, A R
%A Wojdacz, T K
%A Beck, S
%D 2014
%J Bioinformatics
%K MUSTREAD fulltext methylation microarray open-source pipeline quality-control r-language software
%N 3
%P 428-430
%R 10.1093/bioinformatics/btt684
%T ChAMP: 450k Chip Analysis Methylation Pipeline
%U https://www.ncbi.nlm.nih.gov/pubmed/24336642/
%V 30
%X The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org
@article{Morris:2014:Bioinformatics:24336642,
abstract = {The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org},
added-at = {2018-07-08T10:17:26.000+0200},
author = {Morris, T J and Butcher, L M and Feber, A and Teschendorff, A E and Chakravarthy, A R and Wojdacz, T K and Beck, S},
biburl = {https://www.bibsonomy.org/bibtex/2402132aed9a1c99d542ffaf912add14b/marcsaric},
description = {ChAMP: 450k Chip Analysis Methylation Pipeline. - PubMed - NCBI},
doi = {10.1093/bioinformatics/btt684},
interhash = {5dd56aa7927921560db99292a2ae724f},
intrahash = {402132aed9a1c99d542ffaf912add14b},
journal = {Bioinformatics},
keywords = {MUSTREAD fulltext methylation microarray open-source pipeline quality-control r-language software},
month = feb,
number = 3,
pages = {428-430},
pmid = {24336642},
timestamp = {2018-07-08T10:17:26.000+0200},
title = {ChAMP: 450k Chip Analysis Methylation Pipeline},
url = {https://www.ncbi.nlm.nih.gov/pubmed/24336642/},
volume = 30,
year = 2014
}