The purpose of this article is to describe outcomes of intrathecal baclofen therapy for 29 patients with cerebral palsy, focusing on impairments, functional limitations, and disability. Patients received individualized rehabilitation and were followed up to 24 months. The primary outcome measures were the Ashworth Scale and the functional skills and caregiver assistance scales of the Pediatric Evaluation of Disability Inventory (PEDI). Ashworth Scale scores were significantly reduced (P < or = .0005). All areas of functional skills and caregiver assistance improved. Comparing groups of adults and patients less than 18 years, there were no significant differences, but there was a relationship between age and dose. Comparing groups of patients in high and low levels of independent functional mobility, no significant differences were found. These results provide suggestive evidence that the combination of intrathecal baclofen therapy and rehabilitation has positive effects across the dimensions of disablement. This study serves as a basis for high-level scientific studies of these effects.
%0 Journal Article
%1 Awaad2003
%A Awaad, Yasser
%A Tayem, Hassan
%A Munoz, Sharon
%A Ham, Steven
%A Michon, Anne Marie
%A Awaad, Rania
%D 2003
%J J Child Neurol
%K Activities of Daily Living; Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Combined Modality Therapy; Disability Evaluation; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Muscle Spasticity; Neurologic Examination; Outcome and Process Assessment (Health Care); Physical Therapy Modalities
%N 1
%P 26--34
%T Functional assessment following intrathecal baclofen therapy in children with spastic cerebral palsy.
%V 18
%X The purpose of this article is to describe outcomes of intrathecal baclofen therapy for 29 patients with cerebral palsy, focusing on impairments, functional limitations, and disability. Patients received individualized rehabilitation and were followed up to 24 months. The primary outcome measures were the Ashworth Scale and the functional skills and caregiver assistance scales of the Pediatric Evaluation of Disability Inventory (PEDI). Ashworth Scale scores were significantly reduced (P < or = .0005). All areas of functional skills and caregiver assistance improved. Comparing groups of adults and patients less than 18 years, there were no significant differences, but there was a relationship between age and dose. Comparing groups of patients in high and low levels of independent functional mobility, no significant differences were found. These results provide suggestive evidence that the combination of intrathecal baclofen therapy and rehabilitation has positive effects across the dimensions of disablement. This study serves as a basis for high-level scientific studies of these effects.
@article{Awaad2003,
abstract = {The purpose of this article is to describe outcomes of intrathecal baclofen therapy for 29 patients with cerebral palsy, focusing on impairments, functional limitations, and disability. Patients received individualized rehabilitation and were followed up to 24 months. The primary outcome measures were the Ashworth Scale and the functional skills and caregiver assistance scales of the Pediatric Evaluation of Disability Inventory (PEDI). Ashworth Scale scores were significantly reduced (P < or = .0005). All areas of functional skills and caregiver assistance improved. Comparing groups of adults and patients less than 18 years, there were no significant differences, but there was a relationship between age and dose. Comparing groups of patients in high and low levels of independent functional mobility, no significant differences were found. These results provide suggestive evidence that the combination of intrathecal baclofen therapy and rehabilitation has positive effects across the dimensions of disablement. This study serves as a basis for high-level scientific studies of these effects.},
added-at = {2014-07-19T17:50:13.000+0200},
author = {Awaad, Yasser and Tayem, Hassan and Munoz, Sharon and Ham, Steven and Michon, Anne Marie and Awaad, Rania},
biburl = {https://www.bibsonomy.org/bibtex/2412620ac41f57bdfb0d7582ca4eeaae9/ar0berts},
groups = {public},
interhash = {9c6e01c56bc02b95d5d1a2b8de073b71},
intrahash = {412620ac41f57bdfb0d7582ca4eeaae9},
journal = {J Child Neurol},
keywords = {Activities of Daily Living; Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Combined Modality Therapy; Disability Evaluation; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Muscle Spasticity; Neurologic Examination; Outcome and Process Assessment (Health Care); Physical Therapy Modalities},
month = Jan,
number = 1,
pages = {26--34},
pmid = {12661935},
timestamp = {2014-07-19T17:50:13.000+0200},
title = {Functional assessment following intrathecal baclofen therapy in children with spastic cerebral palsy.},
username = {ar0berts},
volume = 18,
year = 2003
}