Evaluation of the Gen-Probe PACE 2 assay for the detection of asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees
BACKGROUND: The LET and Gen-Probe PACE 2 assay are used to screen male arrestees for evidence of infection with chlamydia and gonorrhea in the intake/booking area of the Jefferson Parish Correctional Center. GOAL OF THIS STUDY: To determine the accuracy of the Gen-Probe PACE 2 assay for the detection of asymptomatic infection with Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees. STUDY DESIGN: From December 1993 to March 1994, 196 arrestees younger than 22 years were screened with the Gen-Probe PACE 2 assay and McCoy shell vial culture for Chlamydia trachomatis. From April to October 1994, 444 arrestees of all ages were screened with the Gen-Probe PACE 2 assay and standard culture for Neisseria gonorrhoeae. The sensitivity, specificity, and predictive values of the Gen-Probe PACE 2 assay, compared with culture, were calculated with 95\% confidence intervals. RESULTS: The Gen-Probe PACE 2 assay compared with culture had a sensitivity, specificity, and positive predictive value for Chlamydia trachomatis of 84\%, 99\%, and 93\% and for Neisseria gonorrhoeae of 54\%, 99.5\%, and 78\%. CONCLUSION: The Gen-Probe PACE 2 assay is useful for screening young males in this jail setting and is more accurate for detecting Chlamydia trachomatis compared with Neisseria gonorrhoeae.
%0 Journal Article
%1 beltrami_evaluation_1998
%A Beltrami, J F
%A Farley, T A
%A Hamrick, J T
%A Cohen, D A
%A Martin, D H
%D 1998
%J Sexually Transmitted Diseases
%K Adolescent, Adult, Aged, Chlamydia Evaluation Gonorrhea, Humans, Infections, Louisiana, Male, Mass Middle Neisseria Predictive Prisoners, Screening, Sensitivity Specificity, Studies Tests, Topic, Urethra Value and as gonorrhoeae, of trachomatis,
%N 10
%P 501--504
%T Evaluation of the Gen-Probe PACE 2 assay for the detection of asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees
%U http://www.ncbi.nlm.nih.gov/pubmed/9858343
%V 25
%X BACKGROUND: The LET and Gen-Probe PACE 2 assay are used to screen male arrestees for evidence of infection with chlamydia and gonorrhea in the intake/booking area of the Jefferson Parish Correctional Center. GOAL OF THIS STUDY: To determine the accuracy of the Gen-Probe PACE 2 assay for the detection of asymptomatic infection with Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees. STUDY DESIGN: From December 1993 to March 1994, 196 arrestees younger than 22 years were screened with the Gen-Probe PACE 2 assay and McCoy shell vial culture for Chlamydia trachomatis. From April to October 1994, 444 arrestees of all ages were screened with the Gen-Probe PACE 2 assay and standard culture for Neisseria gonorrhoeae. The sensitivity, specificity, and predictive values of the Gen-Probe PACE 2 assay, compared with culture, were calculated with 95\% confidence intervals. RESULTS: The Gen-Probe PACE 2 assay compared with culture had a sensitivity, specificity, and positive predictive value for Chlamydia trachomatis of 84\%, 99\%, and 93\% and for Neisseria gonorrhoeae of 54\%, 99.5\%, and 78\%. CONCLUSION: The Gen-Probe PACE 2 assay is useful for screening young males in this jail setting and is more accurate for detecting Chlamydia trachomatis compared with Neisseria gonorrhoeae.
@article{beltrami_evaluation_1998,
abstract = {{BACKGROUND:} The {LET} and {Gen-Probe} {PACE} 2 assay are used to screen male arrestees for evidence of infection with chlamydia and gonorrhea in the intake/booking area of the Jefferson Parish Correctional Center. {GOAL} {OF} {THIS} {STUDY:} To determine the accuracy of the {Gen-Probe} {PACE} 2 assay for the detection of asymptomatic infection with Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees. {STUDY} {DESIGN:} From December 1993 to March 1994, 196 arrestees younger than 22 years were screened with the {Gen-Probe} {PACE} 2 assay and {McCoy} shell vial culture for Chlamydia trachomatis. From April to October 1994, 444 arrestees of all ages were screened with the {Gen-Probe} {PACE} 2 assay and standard culture for Neisseria gonorrhoeae. The sensitivity, specificity, and predictive values of the {Gen-Probe} {PACE} 2 assay, compared with culture, were calculated with 95\% confidence intervals. {RESULTS:} The {Gen-Probe} {PACE} 2 assay compared with culture had a sensitivity, specificity, and positive predictive value for Chlamydia trachomatis of 84\%, 99\%, and 93\% and for Neisseria gonorrhoeae of 54\%, 99.5\%, and 78\%. {CONCLUSION:} The {Gen-Probe} {PACE} 2 assay is useful for screening young males in this jail setting and is more accurate for detecting Chlamydia trachomatis compared with Neisseria gonorrhoeae.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Beltrami, J F and Farley, T A and Hamrick, J T and Cohen, D A and Martin, D H},
biburl = {https://www.bibsonomy.org/bibtex/2610d3369eba30ae76c4bbd4fd8664606/jelias},
interhash = {eb51a63fe60dc0cbcc2940dd96bbc48a},
intrahash = {610d3369eba30ae76c4bbd4fd8664606},
issn = {0148-5717},
journal = {Sexually Transmitted Diseases},
keywords = {Adolescent, Adult, Aged, Chlamydia Evaluation Gonorrhea, Humans, Infections, Louisiana, Male, Mass Middle Neisseria Predictive Prisoners, Screening, Sensitivity Specificity, Studies Tests, Topic, Urethra Value and as gonorrhoeae, of trachomatis,},
month = nov,
note = {{PMID:} 9858343},
number = 10,
pages = {501--504},
timestamp = {2011-03-11T10:06:23.000+0100},
title = {Evaluation of the {Gen-Probe} {PACE} 2 assay for the detection of asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in male arrestees},
url = {http://www.ncbi.nlm.nih.gov/pubmed/9858343},
volume = 25,
year = 1998
}