Of the 32 patients with active intractable seizures, 27 had spastic cerebral palsy (CP) and 5 had epilepsy (EP), and all underwent chronic cerebellar stimulation (CCS) (amplitude 1-2 microC/cm2/phase, rate 10-180 pps, duration of implantation 0.5-7 years, average 4.5 years). Grand mal seizures occurred in 23 patients (19 CP, 4 EP); with CCS 17 patients stopped, 4 had a reduction, 3 were unchanged. Petit mal occurred in 9 patients (8 CP, 1 EP); with CCS 4 patients ceased seizuring, 3 reduced and 2 were unchanged. Myoclonic seizures were present in 6 patients (5 CP, 1 EP); with CCS 1 patient stopped, 3 had a reduction while 2 patients were unaffected. Severe psychomotor seizuring affected 2 EP patients, 1 had a marked behavioral improvement and finally stopped seizuring for the past 9 months. Overall, CCS stopped 18 (57\%) of the patients seizuring, reduced a further 9 (28\%), with no effect in 5 patients (15\%).
%0 Journal Article
%1 Davis1983
%A Davis, R.
%A Gray, E.
%A Engle, H.
%A Dusnak, A.
%D 1983
%J Appl Neurophysiol
%K Adolescent; Adult; Cerebellum; Cerebral Palsy; Chi; Child; Electric Stimulation Therapy; Electrodes, Implanted; Epilepsy; Evoked Potentials; Follow-Up Studies; Humans; ld, Preschool
%N 1-4
%P 57--61
%T Reduction of intractable seizures using cerebellar stimulation.
%V 46
%X Of the 32 patients with active intractable seizures, 27 had spastic cerebral palsy (CP) and 5 had epilepsy (EP), and all underwent chronic cerebellar stimulation (CCS) (amplitude 1-2 microC/cm2/phase, rate 10-180 pps, duration of implantation 0.5-7 years, average 4.5 years). Grand mal seizures occurred in 23 patients (19 CP, 4 EP); with CCS 17 patients stopped, 4 had a reduction, 3 were unchanged. Petit mal occurred in 9 patients (8 CP, 1 EP); with CCS 4 patients ceased seizuring, 3 reduced and 2 were unchanged. Myoclonic seizures were present in 6 patients (5 CP, 1 EP); with CCS 1 patient stopped, 3 had a reduction while 2 patients were unaffected. Severe psychomotor seizuring affected 2 EP patients, 1 had a marked behavioral improvement and finally stopped seizuring for the past 9 months. Overall, CCS stopped 18 (57\%) of the patients seizuring, reduced a further 9 (28\%), with no effect in 5 patients (15\%).
@article{Davis1983,
abstract = {Of the 32 patients with active intractable seizures, 27 had spastic cerebral palsy (CP) and 5 had epilepsy (EP), and all underwent chronic cerebellar stimulation (CCS) (amplitude 1-2 microC/cm2/phase, rate 10-180 pps, duration of implantation 0.5-7 years, average 4.5 years). Grand mal seizures occurred in 23 patients (19 CP, 4 EP); with CCS 17 patients stopped, 4 had a reduction, 3 were unchanged. Petit mal occurred in 9 patients (8 CP, 1 EP); with CCS 4 patients ceased seizuring, 3 reduced and 2 were unchanged. Myoclonic seizures were present in 6 patients (5 CP, 1 EP); with CCS 1 patient stopped, 3 had a reduction while 2 patients were unaffected. Severe psychomotor seizuring affected 2 EP patients, 1 had a marked behavioral improvement and finally stopped seizuring for the past 9 months. Overall, CCS stopped 18 (57\%) of the patients seizuring, reduced a further 9 (28\%), with no effect in 5 patients (15\%).},
added-at = {2014-07-19T19:17:56.000+0200},
author = {Davis, R. and Gray, E. and Engle, H. and Dusnak, A.},
biburl = {https://www.bibsonomy.org/bibtex/26bf4e2c94f6438e74cd9458fcf1cc0a4/ar0berts},
groups = {public},
interhash = {39d0316382f1bf4917c14ed2e2f38c71},
intrahash = {6bf4e2c94f6438e74cd9458fcf1cc0a4},
journal = {Appl Neurophysiol},
keywords = {Adolescent; Adult; Cerebellum; Cerebral Palsy; Chi; Child; Electric Stimulation Therapy; Electrodes, Implanted; Epilepsy; Evoked Potentials; Follow-Up Studies; Humans; ld, Preschool},
number = {1-4},
pages = {57--61},
pmid = {6608318},
timestamp = {2014-07-19T19:17:56.000+0200},
title = {Reduction of intractable seizures using cerebellar stimulation.},
username = {ar0berts},
volume = 46,
year = 1983
}