%0 Journal Article %1 Eltamany20144939 %A Eltamany, Enas E. %A Abdelmohsen, Usama Ramadan %A Ibrahim, Amany K. %A Hassanean, Hashim A. %A Hentschel, Ute %A Ahmed, Safwat A. %D 2014 %J Bioorganic & Medicinal Chemistry Letters %K myown %N 21 %P 4939 - 4942 %R http://dx.doi.org/10.1016/j.bmcl.2014.09.040 %T New antibacterial xanthone from the marine sponge-derived Micrococcus sp. \EG45\ %U http://www.sciencedirect.com/science/article/pii/S0960894X14009822 %V 24 %X Abstract Microluside A 4 (19-para-hydroxy benzoyloxy-O-β-d-cellobiosyl), 5 (30-para-hydroxy benzoyloxy-O-β-d-glucopyranosyl) xanthone (1) is a unique O-glycosylated disubstituted xanthone isolated from the broth culture of Micrococcus sp. \EG45\ cultivated from the Red Sea sponge Spheciospongia vagabunda. The structure of microluside A was determined by 1D- and 2D-NMR techniques as well as high resolution tandem mass spectrometry. The antimicrobial activity evaluation showed that 1 exhibited antibacterial potential against Enterococcus faecalis \JH212\ and Staphylococcus aureus \NCTC\ 8325 with \MIC\ values of 10 and 13 μM, respectively.

@article{Eltamany20144939, abstract = {Abstract Microluside A [4 (19-para-hydroxy benzoyloxy-O-β-d-cellobiosyl), 5 (30-para-hydroxy benzoyloxy-O-β-d-glucopyranosyl) xanthone (1)] is a unique O-glycosylated disubstituted xanthone isolated from the broth culture of Micrococcus sp. \{EG45\} cultivated from the Red Sea sponge Spheciospongia vagabunda. The structure of microluside A was determined by 1D- and 2D-NMR techniques as well as high resolution tandem mass spectrometry. The antimicrobial activity evaluation showed that 1 exhibited antibacterial potential against Enterococcus faecalis \{JH212\} and Staphylococcus aureus \{NCTC\} 8325 with \{MIC\} values of 10 and 13 μM, respectively. }, added-at = {2015-04-30T14:02:44.000+0200}, author = {Eltamany, Enas E. and Abdelmohsen, Usama Ramadan and Ibrahim, Amany K. and Hassanean, Hashim A. and Hentschel, Ute and Ahmed, Safwat A.}, biburl = {https://www.bibsonomy.org/bibtex/270b6a0d69856113a73b57789061b3bf2/abdelmohsen}, doi = {http://dx.doi.org/10.1016/j.bmcl.2014.09.040}, interhash = {6131fd5b9eade4a19314e558d37dff46}, intrahash = {70b6a0d69856113a73b57789061b3bf2}, issn = {0960-894X}, journal = {Bioorganic & Medicinal Chemistry Letters }, keywords = {myown}, number = 21, pages = {4939 - 4942}, timestamp = {2015-04-30T14:02:44.000+0200}, title = {New antibacterial xanthone from the marine sponge-derived Micrococcus sp. \{EG45\} }, url = {http://www.sciencedirect.com/science/article/pii/S0960894X14009822}, volume = 24, year = 2014 }