We present an imipenem lysate metallo-beta-lactamase (MBL) functional assay. This assay eliminates false-positive results due to the bactericidal effects of EDTA, can be performed with inexpensive reagents available in most laboratories, and is as accurate as the MBL Etest. It is appropriate for both high-accuracy screens and laboratories in developing countries with limited resources.
%0 Journal Article
%1 tan_new_2008
%A Tan, Jingyuan
%A Pitout, Johann D D
%A Guttman, David S
%D 2008
%J Journal of Clinical Microbiology
%K Agents, Imipenem, Microbial Pseudomonas Resistance, Sensitivity Tests, aeruginosa {Anti-Bacterial} {beta-Lactamases,} {beta-Lactam}
%N 5
%P 1870--2
%R JCM.02175-07
%T New and sensitive assay for determining Pseudomonas aeruginosa metallo-beta-lactamase resistance to imipenem
%U http://www.ncbi.nlm.nih.gov/pubmed/18337388
%V 46
%X We present an imipenem lysate metallo-beta-lactamase (MBL) functional assay. This assay eliminates false-positive results due to the bactericidal effects of EDTA, can be performed with inexpensive reagents available in most laboratories, and is as accurate as the MBL Etest. It is appropriate for both high-accuracy screens and laboratories in developing countries with limited resources.
@article{tan_new_2008,
abstract = {We present an imipenem lysate metallo-beta-lactamase {(MBL)} functional assay. This assay eliminates false-positive results due to the bactericidal effects of {EDTA,} can be performed with inexpensive reagents available in most laboratories, and is as accurate as the {MBL} Etest. It is appropriate for both high-accuracy screens and laboratories in developing countries with limited resources.},
added-at = {2011-03-11T10:05:34.000+0100},
author = {Tan, Jingyuan and Pitout, Johann D D and Guttman, David S},
biburl = {https://www.bibsonomy.org/bibtex/27add63c7d01244bc7700e2306376c8d2/jelias},
doi = {JCM.02175-07},
interhash = {7023d9ed027ac8745cbe37a478b83923},
intrahash = {7add63c7d01244bc7700e2306376c8d2},
issn = {{1098-660X}},
journal = {Journal of Clinical Microbiology},
keywords = {Agents, Imipenem, Microbial Pseudomonas Resistance, Sensitivity Tests, aeruginosa {Anti-Bacterial} {beta-Lactamases,} {beta-Lactam}},
month = may,
note = {{PMID:} 18337388},
number = 5,
pages = {1870--2},
timestamp = {2011-03-11T10:06:47.000+0100},
title = {New and sensitive assay for determining Pseudomonas aeruginosa metallo-beta-lactamase resistance to imipenem},
url = {http://www.ncbi.nlm.nih.gov/pubmed/18337388},
volume = 46,
year = 2008
}