%0 Journal Article %1 ISI:000301964700020 %A Ahadi, Somayeh %A Abaszadeh, Maryam %A Khavasi, Hamid Reza %A Bazgir, Ayoob %C THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND %D 2012 %I PERGAMON-ELSEVIER SCIENCE LTD %J TETRAHEDRON %K 2-Aminopyridinium} Barbiturate Pyrimidine-tetraones; acid; salt; {Barbituric %N 13 %P 2906-2916 %R 10.1016/j.tet.2012.01.069 %T An efficient three-component synthesis of new barbiturate salts %V 68 %X An efficient synthesis of new barbiturate salts consist of 2-aminopyridinium moiety by an uncatalyzed three-component condensation reaction of C-H acids, pyrimidine-tetraones, and 2-aminopyridines in refluxing chloroform is reported. The reaction of pyrimidine-tetraones and 2-aminopyridines with ninhydrin in the formation of new barbiturate salts consist of 2-aminopyridinium moiety is also investigated. (C) 2012 Elsevier Ltd. All rights reserved.

@article{ISI:000301964700020, abstract = {{An efficient synthesis of new barbiturate salts consist of 2-aminopyridinium moiety by an uncatalyzed three-component condensation reaction of C-H acids, pyrimidine-tetraones, and 2-aminopyridines in refluxing chloroform is reported. The reaction of pyrimidine-tetraones and 2-aminopyridines with ninhydrin in the formation of new barbiturate salts consist of 2-aminopyridinium moiety is also investigated. (C) 2012 Elsevier Ltd. All rights reserved.}}, added-at = {2017-05-10T15:29:29.000+0200}, address = {{THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND}}, affiliation = {{Bazgir, A (Reprint Author), Shahid Beheshti Univ, Dept Chem, Gen Campus, Tehran 1983963113, Iran. Ahadi, Somayeh; Abaszadeh, Maryam; Khavasi, Hamid Reza; Bazgir, Ayoob, Shahid Beheshti Univ, Dept Chem, Tehran 1983963113, Iran.}}, author = {Ahadi, Somayeh and Abaszadeh, Maryam and Khavasi, Hamid Reza and Bazgir, Ayoob}, author-email = {{a\_bazgir@sbu.ac.ir}}, biburl = {https://www.bibsonomy.org/bibtex/27c7985700c2243aabebc88ae7e68c61e/hkhavasi}, cited-references = {{Abbiati G, 2005, J ORG CHEM, V70, P6454, DOI 10.1021/jo050882q. Abboub F, 2001, J SOC ALGER CHIM, V11, P223. Ahadi S, 2010, J HETEROCYCLIC CHEM, V47, P1090, DOI 10.1002/jhet.437. Archana S., 2002, ARZNEIM FORSCH DRUG, V52, P787. Archana S., 2003, ARZNEIM FORSCH DRUG, V53, P301. Bertolasi V, 2001, NEW J CHEM, V25, P408, DOI 10.1039/b008262g. Bienayme H, 2000, CHEM-EUR J, V6, P3321, DOI 10.1002/1521-3765(20000915)6:18<3321::AID-CHEM3321>3.0.CO;2-A. Braga D, 2007, NEW J CHEM, V31, P1935, DOI 10.1039/b704772j. Calas M, 2007, J MED CHEM, V50, P6307, DOI 10.1021/jm0704752. 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Patent, Patent No. {[}WO99= 25699, 9925699, 9925699(A1): 19990527].}}, doc-delivery-number = {{914PW}}, doi = {{10.1016/j.tet.2012.01.069}}, funding-acknowledgement = {{Research Council of Shahid Beheshti, University}}, funding-text = {{We gratefully acknowledge financial support from the Research Council of Shahid Beheshti, University.}}, interhash = {f5a55b927b621fa3e8733def21e11c9d}, intrahash = {7c7985700c2243aabebc88ae7e68c61e}, issn = {{0040-4020}}, journal = {{TETRAHEDRON}}, journal-iso = {{Tetrahedron}}, keywords = {2-Aminopyridinium} Barbiturate Pyrimidine-tetraones; acid; salt; {Barbituric}, keywords-plus = {{ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; 1,3-DIMETHYLBARBITURIC ACID; AMINOPYRIDINIUM SALTS; URIDINE PHOSPHORYLASE; ZWITTERIONIC SALTS; FACILE SYNTHESIS; DRUG DISCOVERY; MELDRUM ACID; INHIBITORS}}, language = {{English}}, month = {{APR 1}}, number = {{13}}, number-of-cited-references = {{49}}, pages = {{2906-2916}}, publisher = {{PERGAMON-ELSEVIER SCIENCE LTD}}, research-areas = {{Chemistry}}, times-cited = {{4}}, timestamp = {2017-05-10T15:29:29.000+0200}, title = {{An efficient three-component synthesis of new barbiturate salts}}, type = {{Article}}, unique-id = {{ISI:000301964700020}}, usage-count-last-180-days = {{2}}, usage-count-since-2013 = {{9}}, volume = {{68}}, web-of-science-categories = {{Chemistry, Organic}}, year = {{2012}} }