%0 Journal Article %1 Kelley2015MOST %A Kelley, James J. %A Lane, Anatoliy %A Li, Xiaowei %A Mutthoju, Brahmaji %A Maor, Shay %A Egen, Dennis %A Lun, Desmond S. %D 2015 %J Bioinformatics (Oxford, England) %K in-silico metabolic-engineering software %N 4 %P 610--611 %T MOST: a software environment for constraint-based metabolic modeling and strain design. %U http://view.ncbi.nlm.nih.gov/pubmed/25677126 %V 31 %X MOST (metabolic optimization and simulation tool) is a software package that implements GDBB (genetic design through branch and bound) in an intuitive user-friendly interface with excel-like editing functionality, as well as implementing FBA (flux balance analysis), and supporting systems biology markup language and comma-separated values files. GDBB is currently the fastest algorithm for finding gene knockouts predicted by FBA to increase production of desired products, but GDBB has only been available on a command line interface, which is difficult to use for those without programming knowledge, until the release of MOST. MOST is distributed for free on the GNU General Public License. The software and full documentation are available at http://most.ccib.rutgers.edu/. dslun@rutgers.edu. \copyright The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

@article{Kelley2015MOST, abstract = {{MOST} (metabolic optimization and simulation tool) is a software package that implements {GDBB} (genetic design through branch and bound) in an intuitive user-friendly interface with excel-like editing functionality, as well as implementing {FBA} (flux balance analysis), and supporting systems biology markup language and comma-separated values files. {GDBB} is currently the fastest algorithm for finding gene knockouts predicted by {FBA} to increase production of desired products, but {GDBB} has only been available on a command line interface, which is difficult to use for those without programming knowledge, until the release of {MOST}. {MOST} is distributed for free on the {GNU} General Public License. The software and full documentation are available at http://most.ccib.rutgers.edu/. dslun@rutgers.edu. {\copyright} The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.}, added-at = {2018-12-02T16:09:07.000+0100}, author = {Kelley, James J. and Lane, Anatoliy and Li, Xiaowei and Mutthoju, Brahmaji and Maor, Shay and Egen, Dennis and Lun, Desmond S.}, biburl = {https://www.bibsonomy.org/bibtex/2888fd140b5004b310ff8e7fbb51aace7/karthikraman}, citeulike-article-id = {13582499}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/25677126}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=25677126}, day = 15, interhash = {ee35dd77e14abf43ce10de78b1cff1df}, intrahash = {888fd140b5004b310ff8e7fbb51aace7}, issn = {1367-4811}, journal = {Bioinformatics (Oxford, England)}, keywords = {in-silico metabolic-engineering software}, month = feb, number = 4, pages = {610--611}, pmid = {25677126}, posted-at = {2015-04-15 10:17:06}, priority = {2}, timestamp = {2018-12-02T16:09:07.000+0100}, title = {{MOST}: a software environment for constraint-based metabolic modeling and strain design.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/25677126}, volume = 31, year = 2015 }