%0 Journal Article %1 ISI:000312122500005 %A Rahmati, Abbas %A Kenarkoohi, Tahmineh %A Khavasi, Hamid Reza %C 1155 16TH ST, NW, WASHINGTON, DC 20036 USA %D 2012 %I AMER CHEMICAL SOC %J ACS COMBINATORIAL SCIENCE %K 1,4-dihydropyridines} isatin; {spirooxindole; %N 12 %P 657-664 %R 10.1021/co300047j %T Synthesis of 2,6 `-Dioxo-1 `,5 `,6 `,7 `-tetrahydrospiroindoline-3,4 `-pyrazolo3,4-bpyridine-5 `-carbonitriles via a One-Pot, Three-Component Reaction in Water %V 14 %X A one-pot, three-component condensation reaction of an isatin, aminopyrazole, and alkyl cyanoacetate in water to give 2,6'-dioxo-1',5',6',7'-tetrahydrospiroindoline-3,4'-pyrazolo3,4-b pyridine-5'-carbonitrile with good yields, at 90 degrees C, using a Et3N as catalyst, is described.

@article{ISI:000312122500005, abstract = {{A one-pot, three-component condensation reaction of an isatin, aminopyrazole, and alkyl cyanoacetate in water to give 2,6'-dioxo-1',5',6',7'-tetrahydrospiro{[}indoline-3,4'-pyrazolo{[}3,4-b] pyridine]-5'-carbonitrile with good yields, at 90 degrees C, using a Et3N as catalyst, is described.}}, added-at = {2017-05-10T15:29:29.000+0200}, address = {{1155 16TH ST, NW, WASHINGTON, DC 20036 USA}}, affiliation = {{Rahmati, A (Reprint Author), Univ Isfahan, Dept Chem, POB 81746-73441, Esfahan, Iran. Rahmati, Abbas; Kenarkoohi, Tahmineh, Univ Isfahan, Dept Chem, Esfahan, Iran. Khavasi, Hamid Reza, Shahid Beheshti Univ, Dept Chem, Tehran 1983963113, Iran.}}, author = {Rahmati, Abbas and Kenarkoohi, Tahmineh and Khavasi, Hamid Reza}, author-email = {{a.rahmati@sci.ui.ac.ir}}, biburl = {https://www.bibsonomy.org/bibtex/28b43e8aa763003d9552324b61ac4734f/hkhavasi}, cited-references = {{Abdel-Rahman A. H., 2004, BIOORGAN MED CHEM, V12, P2483. 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Saggar S, 2007, US Patent Application, Patent No. {[}2,007,021,442, 2007021442].}}, doc-delivery-number = {{051JM}}, doi = {{10.1021/co300047j}}, funding-acknowledgement = {{Research Council of the University of Isfahan}}, funding-text = {{We gratefully acknowledge financial support from the Research Council of the University of Isfahan.}}, interhash = {5003ee092f5278b4367e73c2d3eccfee}, intrahash = {8b43e8aa763003d9552324b61ac4734f}, issn = {{2156-8952}}, journal = {{ACS COMBINATORIAL SCIENCE}}, journal-iso = {{ACS Comb. Sci.}}, keywords = {1,4-dihydropyridines} isatin; {spirooxindole;}, keywords-plus = {{SPIROOXINDOLE DERIVATIVES; PHALARIS-COERULESCENS; INHIBITORS; ALKALOIDS; ISATINS; SPIROTRYPROSTATIN; DISCOVERY; ANALOGS; SERIES; SAR}}, language = {{English}}, month = {{DEC}}, number = {{12}}, number-of-cited-references = {{43}}, pages = {{657-664}}, publisher = {{AMER CHEMICAL SOC}}, research-areas = {{Chemistry; Pharmacology \& Pharmacy}}, times-cited = {{15}}, timestamp = {2017-05-10T15:29:29.000+0200}, title = {{Synthesis of 2,6 `-Dioxo-1 `,5 `,6 `,7 `-tetrahydrospiro{[}indoline-3,4 `-pyrazolo{[}3,4-b]pyridine]-5 `-carbonitriles via a One-Pot, Three-Component Reaction in Water}}, type = {{Article}}, unique-id = {{ISI:000312122500005}}, usage-count-last-180-days = {{2}}, usage-count-since-2013 = {{15}}, volume = {{14}}, web-of-science-categories = {{Chemistry, Applied; Chemistry, Medicinal; Chemistry, Multidisciplinary}}, year = {{2012}} }