%0 Journal Article %1 Kues:1992:Genes-Dev:1348484 %A Kües, U %A Richardson, W V %A Tymon, A M %A Mutasa, E S %A Göttgens, B %A Gaubatz, S %A Gregoriades, A %A Casselton, L A %D 1992 %J Genes Dev %K gaubatz %N 4 %P 568-577 %R 10.1101/gad.6.4.568 %T The combination of dissimilar alleles of the A alpha and A beta gene complexes, whose proteins contain homeo domain motifs, determines sexual development in the mushroom Coprinus cinereus %U https://pubmed.ncbi.nlm.nih.gov/1348484/ %V 6 %X The A mating-type factor is one of two gene complexes that allows mating cells of the mushroom Coprinus cinereus to recognize self from nonself and to regulate a pathway of sexual development that leads to meiosis and sporulation. We have identified seven A genes separated into two subcomplexes corresponding to the classical A alpha and A beta loci. Four genes, one alpha and three beta, all coding for proteins with a homeo domain-related motif, determine A-factor specificity; their allelic forms are so different in sequence that they do not cross-hybridize. It requires only one of these four genes to be heteroallelic in a cell to trigger A-regulated sexual development, and it is the different combinations of their alleles that generate the multiple A factors found in nature. The other three genes cause no change in cell morphology and may regulate the activity of the four specificity genes.

@article{Kues:1992:Genes-Dev:1348484, abstract = {The A mating-type factor is one of two gene complexes that allows mating cells of the mushroom Coprinus cinereus to recognize self from nonself and to regulate a pathway of sexual development that leads to meiosis and sporulation. We have identified seven A genes separated into two subcomplexes corresponding to the classical A alpha and A beta loci. Four genes, one alpha and three beta, all coding for proteins with a homeo domain-related motif, determine A-factor specificity; their allelic forms are so different in sequence that they do not cross-hybridize. It requires only one of these four genes to be heteroallelic in a cell to trigger A-regulated sexual development, and it is the different combinations of their alleles that generate the multiple A factors found in nature. The other three genes cause no change in cell morphology and may regulate the activity of the four specificity genes.}, added-at = {2020-08-29T07:58:56.000+0200}, author = {K{\"u}es, U and Richardson, W V and Tymon, A M and Mutasa, E S and G{\"o}ttgens, B and Gaubatz, S and Gregoriades, A and Casselton, L A}, biburl = {https://www.bibsonomy.org/bibtex/28e6137c1e3a360f9dea05fbb7f1135aa/bcz-wue}, description = {The combination of dissimilar alleles of the A alpha and A beta gene complexes, whose proteins contain homeo domain motifs, determines sexual development in the mushroom Coprinus cinereus - PubMed}, doi = {10.1101/gad.6.4.568}, interhash = {2310ee76d856833855e936a42ac93ec3}, intrahash = {8e6137c1e3a360f9dea05fbb7f1135aa}, journal = {Genes Dev}, keywords = {gaubatz}, month = apr, number = 4, pages = {568-577}, pmid = {1348484}, timestamp = {2020-08-29T07:58:56.000+0200}, title = {The combination of dissimilar alleles of the A alpha and A beta gene complexes, whose proteins contain homeo domain motifs, determines sexual development in the mushroom Coprinus cinereus}, url = {https://pubmed.ncbi.nlm.nih.gov/1348484/}, volume = 6, year = 1992 }