%0 Journal Article %1 WOS:000534500000001 %A Pazin, Wallance M %A Furini, Leonardo N %A Solovyeva, Vita %A Lemma, Tibebe %A Rubira, Rafael J G %A Jorgensen, Bjarke %A Constantino, Carlos J L %A Brewer, Jonathan R %C 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA %D 2020 %I SAGE PUBLICATIONS INC %J APPLIED SPECTROSCOPY %K C; CARS Raman SERS; imaging microscopy; propolis; scattering; spectroscopy; surface-enhanced techniques} {Artepillin %N 7 %P 751-757 %R 10.1177/0003702820904456, Early Access Date = APR 2020 %T Vibrational Spectroscopic Characterization and Coherent Anti-Stokes Raman Spectroscopy (CARS) Imaging of Artepillin C %V 74 %X In the following work, the vibrational spectroscopic characteristics of artepillin C are reported by means of Fourier transform infrared (FT-IR) and Raman spectroscopies, surface-enhanced Raman scattering (SERS), and coherent anti-Stokes Raman scattering (CARS) microscopy. Artepillin C is an interesting compound due to its pharmacological properties, including antitumor activity. It is found as the major component of Brazilian green propolis, a resinous mixture produced by bees to protect their hives against intruders. Vibrational spectroscopic techniques have shown a strong peak at 1599 cm(-1), assigned to C=C stretching vibrations from the aromatic ring of artepillin C. From these data, direct visualization of artepillin C could be assessed by means of CARS microscopy, showing differences in the film hydration obtained for its neutral and deprotonated states. Raman-based methods show potential to visualize the uptake and action of artepillin C in biological systems, triggering its interaction with biological systems that are needed to understand its mechanism of action.

@article{WOS:000534500000001, abstract = {In the following work, the vibrational spectroscopic characteristics of artepillin C are reported by means of Fourier transform infrared (FT-IR) and Raman spectroscopies, surface-enhanced Raman scattering (SERS), and coherent anti-Stokes Raman scattering (CARS) microscopy. Artepillin C is an interesting compound due to its pharmacological properties, including antitumor activity. It is found as the major component of Brazilian green propolis, a resinous mixture produced by bees to protect their hives against intruders. Vibrational spectroscopic techniques have shown a strong peak at 1599 cm(-1), assigned to C=C stretching vibrations from the aromatic ring of artepillin C. From these data, direct visualization of artepillin C could be assessed by means of CARS microscopy, showing differences in the film hydration obtained for its neutral and deprotonated states. Raman-based methods show potential to visualize the uptake and action of artepillin C in biological systems, triggering its interaction with biological systems that are needed to understand its mechanism of action.}, added-at = {2022-05-23T20:00:14.000+0200}, address = {2455 TELLER RD, THOUSAND OAKS, CA 91320 USA}, author = {Pazin, Wallance M and Furini, Leonardo N and Solovyeva, Vita and Lemma, Tibebe and Rubira, Rafael J G and Jorgensen, Bjarke and Constantino, Carlos J L and Brewer, Jonathan R}, biburl = {https://www.bibsonomy.org/bibtex/29d89178f7423bf1cad0f6aaf02ce03d9/ppgfis_ufc_br}, doi = {10.1177/0003702820904456, Early Access Date = APR 2020}, interhash = {78094d83134c5df4271a9c87f61a72a1}, intrahash = {9d89178f7423bf1cad0f6aaf02ce03d9}, issn = {0003-7028}, journal = {APPLIED SPECTROSCOPY}, keywords = {C; CARS Raman SERS; imaging microscopy; propolis; scattering; spectroscopy; surface-enhanced techniques} {Artepillin}, number = 7, pages = {751-757}, publisher = {SAGE PUBLICATIONS INC}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Vibrational Spectroscopic Characterization and Coherent Anti-Stokes Raman Spectroscopy (CARS) Imaging of Artepillin C}, tppubtype = {article}, volume = 74, year = 2020 }