%0 Journal Article %1 Ingemarsson1997 %A Ingemarsson, I. %A Herbst, A. %A Thorngren-Jerneck, K. %D 1997 %J Br J Obstet Gynaecol %K Acidosis; Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child Development; Developmental Disabilities; Female; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Male; Pregnancy; Prognosis; Sex Fac; Speech Disorders; Umbilical Arteries; tors %N 10 %P 1123--1127 %T Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities. %V 104 %X OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH < 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome.

@article{Ingemarsson1997, abstract = {OBJECTIVE: To study the outcome after acidaemia at term birth, and the relation to gender and duration of pathological fetal heart rate changes. DESIGN: Population based study of 154 infants with umbilical artery pH < 7.05 at term birth. Neonatal outcome and the result of developmental screening at age four years were compared with a control group with pH > 7.10. Fetal heart rate traces in infants with acidaemia were reviewed, and the relation between duration of fetal heart rate changes and outcome was analysed. RESULTS: Of the 154 newborns with acidaemia at birth, 10 had encephalopathy, of which two died and two developed cerebral palsy. Nine of these 10 infants were boys, and eight had pH < 7.00. Male newborns (n = 39) more often had pronounced acidaemia (pH < 7.00) than females (n = 22). Although few infants had severe impairment, infants born with acidaemia significantly more often had speech problems at follow up than controls (19/102 versus 8/98; P = 0.03). In infants with acidaemia, duration of abnormal fetal heart rate changes was significantly associated with neonatal encephalopathy and speech problems at age four years. CONCLUSIONS: Acidaemia at term birth was associated with neonatal encephalopathy and with speech problems at four years of age. Boys had more often pronounced acidaemia and a complicated course. A protracted abnormal fetal heart rate trace was associated with poor outcome.}, added-at = {2014-07-19T20:29:34.000+0200}, author = {Ingemarsson, I. and Herbst, A. and Thorngren-Jerneck, K.}, biburl = {https://www.bibsonomy.org/bibtex/2aac5e348f8c4536616c9f8323477fb28/ar0berts}, groups = {public}, interhash = {e79d20a9d122cb31b2307760c92608f0}, intrahash = {aac5e348f8c4536616c9f8323477fb28}, journal = {Br J Obstet Gynaecol}, keywords = {Acidosis; Attention Deficit Disorder with Hyperactivity; Brain Diseases; Cerebral Palsy; Child Development; Developmental Disabilities; Female; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Male; Pregnancy; Prognosis; Sex Fac; Speech Disorders; Umbilical Arteries; tors}, month = Oct, number = 10, pages = {1123--1127}, pmid = {9332988}, timestamp = {2014-07-19T20:29:34.000+0200}, title = {Long term outcome after umbilical artery acidaemia at term birth: influence of gender and duration of fetal heart rate abnormalities.}, username = {ar0berts}, volume = 104, year = 1997 }