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Evolving a Hybrid Model of a Fed-batch Fermentation Process

, , , , and . Chemical Engineering, Newcastle University, UK, (1996)

Abstract

This paper presents a novel method for the system identification of the fed-batch fermentation process defined in the problem statement of the Biotechnological Control Forum Modelling and Control Competition. The identification methodology involves a hybrid of mechanistic modelling and Genetic Programming techniques. It provides an accurate model of the system which should be extremely useful in both the optimisation and control of this process. The performance of the model as a 25 time unit ahead predictor of product concentration (on unseen verification data) is such that the root mean square error between the actual and predicted output is less than 5% over the range of interest.

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