Putative etiology was studied in 991 patients with symptomatic localization-related epilepsies seen in a university hospital in South India. They formed 39\% of patients with various types of epilepsies and epileptic syndromes seen during the study period. Seizure occurred in close temporal association with an acute central nervous system (CNS) insult in 53\% of patients. Infections of CNS including single CT enhancing lesion (SCTEL) accounted for 77\% of patients with acute symptomatic epilepsy. Cerebrovascular diseases were the risk factors in 48\% of patients with remote symptomatic epilepsy. Neurocysticercosis, SCTEL and small single cerebral calcific CT lesion (SSCCCTL) together accounted for 40\% of etiological factors and neurotuberculosis for 10\%. Infections of the central nervous system and SCTEL together were the putative risk factors in 52\% of patients aged < or =40 years. Cerebrovascular diseases were the etiological factors in 64\% of patients aged >40 years. Neurological handicaps from birth manifested by mental retardation and/or cerebral palsy was the feature in 21\% of children. The type of seizure was either simple partial or complex partial with or without secondary generalization in 76\% of patients. The remaining patients presented with either generalized tonic clonic seizures or unlocalized seizures. Localization to a single site of seizure origin proposed by the International League Against Epilepsy (ILAE) was possible in only 67.5\% of patients. The most readily identifiable was motor cortex. In patients with unlocalized or generalized seizures the type of pathology was diffuse in 17\% of patients and in 48.5\% of patients, the lesion was located in the frontal brontoparietal lobe.
%0 Journal Article
%1 Murthy1998
%A Murthy, J. M.
%A Yangala, R.
%D 1998
%J J Neurol Sci
%K Adolescent; Adult; Aged; Aged, 80 and over; Calcinosis; Cerebral Palsy; Cerebrovascular Disorders; Child; Child, Preschool; Cysticercosis; Electroencephalography; Encephalitis; Epilepsies, Partial; Female; Humans; India; Male; Middle Prevalence; Prospective Studies; Tomography, X-Ray Computed; Tuberculosis, Meningeal
%N 1
%P 65--70
%T Etiological spectrum of symptomatic localization related epilepsies: a study from South India.
%V 158
%X Putative etiology was studied in 991 patients with symptomatic localization-related epilepsies seen in a university hospital in South India. They formed 39\% of patients with various types of epilepsies and epileptic syndromes seen during the study period. Seizure occurred in close temporal association with an acute central nervous system (CNS) insult in 53\% of patients. Infections of CNS including single CT enhancing lesion (SCTEL) accounted for 77\% of patients with acute symptomatic epilepsy. Cerebrovascular diseases were the risk factors in 48\% of patients with remote symptomatic epilepsy. Neurocysticercosis, SCTEL and small single cerebral calcific CT lesion (SSCCCTL) together accounted for 40\% of etiological factors and neurotuberculosis for 10\%. Infections of the central nervous system and SCTEL together were the putative risk factors in 52\% of patients aged < or =40 years. Cerebrovascular diseases were the etiological factors in 64\% of patients aged >40 years. Neurological handicaps from birth manifested by mental retardation and/or cerebral palsy was the feature in 21\% of children. The type of seizure was either simple partial or complex partial with or without secondary generalization in 76\% of patients. The remaining patients presented with either generalized tonic clonic seizures or unlocalized seizures. Localization to a single site of seizure origin proposed by the International League Against Epilepsy (ILAE) was possible in only 67.5\% of patients. The most readily identifiable was motor cortex. In patients with unlocalized or generalized seizures the type of pathology was diffuse in 17\% of patients and in 48.5\% of patients, the lesion was located in the frontal brontoparietal lobe.
@article{Murthy1998,
abstract = {Putative etiology was studied in 991 patients with symptomatic localization-related epilepsies seen in a university hospital in South India. They formed 39\% of patients with various types of epilepsies and epileptic syndromes seen during the study period. Seizure occurred in close temporal association with an acute central nervous system (CNS) insult in 53\% of patients. Infections of CNS including single CT enhancing lesion (SCTEL) accounted for 77\% of patients with acute symptomatic epilepsy. Cerebrovascular diseases were the risk factors in 48\% of patients with remote symptomatic epilepsy. Neurocysticercosis, SCTEL and small single cerebral calcific CT lesion (SSCCCTL) together accounted for 40\% of etiological factors and neurotuberculosis for 10\%. Infections of the central nervous system and SCTEL together were the putative risk factors in 52\% of patients aged < or =40 years. Cerebrovascular diseases were the etiological factors in 64\% of patients aged >40 years. Neurological handicaps from birth manifested by mental retardation and/or cerebral palsy was the feature in 21\% of children. The type of seizure was either simple partial or complex partial with or without secondary generalization in 76\% of patients. The remaining patients presented with either generalized tonic clonic seizures or unlocalized seizures. Localization to a single site of seizure origin proposed by the International League Against Epilepsy (ILAE) was possible in only 67.5\% of patients. The most readily identifiable was motor cortex. In patients with unlocalized or generalized seizures the type of pathology was diffuse in 17\% of patients and in 48.5\% of patients, the lesion was located in the frontal brontoparietal lobe.},
added-at = {2014-07-19T20:49:39.000+0200},
author = {Murthy, J. M. and Yangala, R.},
biburl = {https://www.bibsonomy.org/bibtex/2bef96be56e9fa27abd7e303a02487b81/ar0berts},
groups = {public},
interhash = {dd7406c0149d2d05d3d93db5620cef83},
intrahash = {bef96be56e9fa27abd7e303a02487b81},
journal = {J Neurol Sci},
keywords = {Adolescent; Adult; Aged; Aged, 80 and over; Calcinosis; Cerebral Palsy; Cerebrovascular Disorders; Child; Child, Preschool; Cysticercosis; Electroencephalography; Encephalitis; Epilepsies, Partial; Female; Humans; India; Male; Middle Prevalence; Prospective Studies; Tomography, X-Ray Computed; Tuberculosis, Meningeal},
month = Jun,
number = 1,
pages = {65--70},
pii = {S0022-510X(98)00093-8},
pmid = {9667780},
timestamp = {2014-07-19T20:49:39.000+0200},
title = {Etiological spectrum of symptomatic localization related epilepsies: a study from South India.},
username = {ar0berts},
volume = 158,
year = 1998
}