%0 Journal Article %1 Scott1990 %A Scott, J. P. %A Fradet, G. %A Smyth, R. L. %A Solis, E. %A Higenbottam, T. W. %A Wallwork, J. %D 1990 %J Eur J Cardiothorac Surg %K transplantation antifolates pneumonia prophylaxis %N 4 %P 197--200; discussion 201 %R 10.1016/1010-7940(90)90004-J %T Management following heart and lung transplantation: five years experience. %U http://dx.doi.org/10.1016/1010-7940(90)90004-J %V 4 %X Since April 1984, 70 patients have received heart-lung transplants at our institution. Actuarial survival is 76\% at 1 year and 68\% at 2 years. All but 4 surviving patients have an unrestricted life style. Rejection was confirmed by lung transbronchial biopsy (TBB) on 277 occasions in 66 patients. Forty-two percent of episodes occurred within 1 month of surgery. Eight patients have developed evidence of chronic rejection with progressive irreversible fall in FEV1, of whom 4 have died or undergone single lung retransplantation. Seven patients had primary cytomegalovirus (CMV) of whom 4 patients died. Eight patients developed pneumocystis pneumonia of whom 1 died. Seven episodes of herpes simplex pneumonitis occurred of which one episode was fatal. Heart-lung transplantation is a valuable treatment for terminal cardiopulmonary disease and offers increasing hope of long-term survival.

@article{Scott1990, abstract = {Since April 1984, 70 patients have received heart-lung transplants at our institution. Actuarial survival is 76\% at 1 year and 68\% at 2 years. All but 4 surviving patients have an unrestricted life style. Rejection was confirmed by lung transbronchial biopsy (TBB) on 277 occasions in 66 patients. Forty-two percent of episodes occurred within 1 month of surgery. Eight patients have developed evidence of chronic rejection with progressive irreversible fall in FEV1, of whom 4 have died or undergone single lung retransplantation. Seven patients had primary cytomegalovirus (CMV) of whom 4 patients died. Eight patients developed pneumocystis pneumonia of whom 1 died. Seven episodes of herpes simplex pneumonitis occurred of which one episode was fatal. Heart-lung transplantation is a valuable treatment for terminal cardiopulmonary disease and offers increasing hope of long-term survival.}, added-at = {2012-06-16T03:51:50.000+0200}, author = {Scott, J. P. and Fradet, G. and Smyth, R. L. and Solis, E. and Higenbottam, T. W. and Wallwork, J.}, biburl = {https://www.bibsonomy.org/bibtex/2ca64f2530d13a280f67465a9da57a5de/aorchid}, description = {Journal is not accessible at UCLA and they do not offer this one for free even though it is so old.}, doi = {10.1016/1010-7940(90)90004-J}, groups = {public}, institution = {Heart-Lung Transplant Research Unit, Papworth Hospital, Cambridge, UK.}, interhash = {7f95ff8f82bb5e816f745b0c9526510c}, intrahash = {ca64f2530d13a280f67465a9da57a5de}, journal = {Eur J Cardiothorac Surg}, keywords = {transplantation antifolates pneumonia prophylaxis}, language = {eng}, medline-pst = {ppublish}, number = 4, pages = {197--200; discussion 201}, pmid = {2159311}, timestamp = {2012-06-16T03:51:50.000+0200}, title = {Management following heart and lung transplantation: five years experience.}, url = {http://dx.doi.org/10.1016/1010-7940(90)90004-J}, username = {aorchid}, volume = 4, year = 1990 }