%0 Journal Article %1 Nelson2001 %A Nelson, M. N. %A White-Traut, R. C. %A Vasan, U. %A Silvestri, J. %A Comiskey, E. %A Meleedy-Rey, P. %A Littau, S. %A Gu, G. %A Patel, M. %D 2001 %J J Child Neurol %K Birth Injuries; Central Nervous System; Cerebral Palsy; Child Development; Female; Humans; Infant; Infant, Newborn; Premature; Intervention Studies; Leukomalacia, Periventricular; Male; Mother-Child Relations; Motor Skills Disorders; Prognosis; Risk Factors; Sensory Thresholds; Treatment Outcome %N 7 %P 493--498 %T One-year outcome of auditory-tactile-visual-vestibular intervention in the neonatal intensive care unit: effects of severe prematurity and central nervous system injury. %V 16 %X Thirty-seven infants with severe central nervous system injury or extreme prematurity were randomly assigned to a multisensory (auditory-tactile-visual-vestibular) intervention or control group. Intervention began in the hospital at 33 weeks' postconceptional age and continued twice daily in the home until 2 months' corrected age. Mother-infant interactions during feedings were videotaped, and the Bayley Scales of Infant Development were administered. Control mothers stimulated their infants more during feeding, but these significant differences dissipated by 4 months. The presence of periventricular leukomalacia was associated with significantly poorer mental development, regardless of group assignment. Experimental infants tended to exhibit better motor and mental performance and had 23\% fewer cerebral palsy diagnoses at 1 year, but these trends were not statistically significant. The type of brain injury was more important in determining 1-year developmental outcome than type of postnatal experience, suggesting that periventricular leukomalacia presents a major challenge for infant development.

@article{Nelson2001, abstract = {Thirty-seven infants with severe central nervous system injury or extreme prematurity were randomly assigned to a multisensory (auditory-tactile-visual-vestibular) intervention or control group. Intervention began in the hospital at 33 weeks' postconceptional age and continued twice daily in the home until 2 months' corrected age. Mother-infant interactions during feedings were videotaped, and the Bayley Scales of Infant Development were administered. Control mothers stimulated their infants more during feeding, but these significant differences dissipated by 4 months. The presence of periventricular leukomalacia was associated with significantly poorer mental development, regardless of group assignment. Experimental infants tended to exhibit better motor and mental performance and had 23\% fewer cerebral palsy diagnoses at 1 year, but these trends were not statistically significant. The type of brain injury was more important in determining 1-year developmental outcome than type of postnatal experience, suggesting that periventricular leukomalacia presents a major challenge for infant development.}, added-at = {2014-07-19T20:54:15.000+0200}, author = {Nelson, M. N. and White-Traut, R. C. and Vasan, U. and Silvestri, J. and Comiskey, E. and Meleedy-Rey, P. and Littau, S. and Gu, G. and Patel, M.}, biburl = {https://www.bibsonomy.org/bibtex/2d70306408168b202de16c2c18684828a/ar0berts}, groups = {public}, interhash = {0a8187859d3bcb1ef8c0103b724729af}, intrahash = {d70306408168b202de16c2c18684828a}, journal = {J Child Neurol}, keywords = {Birth Injuries; Central Nervous System; Cerebral Palsy; Child Development; Female; Humans; Infant; Infant, Newborn; Premature; Intervention Studies; Leukomalacia, Periventricular; Male; Mother-Child Relations; Motor Skills Disorders; Prognosis; Risk Factors; Sensory Thresholds; Treatment Outcome}, month = Jul, number = 7, pages = {493--498}, pmid = {11453445}, timestamp = {2014-07-19T20:54:15.000+0200}, title = {One-year outcome of auditory-tactile-visual-vestibular intervention in the neonatal intensive care unit: effects of severe prematurity and central nervous system injury.}, username = {ar0berts}, volume = 16, year = 2001 }