Development of the human auditory brainstem is thought to be primarily
complete by the age of approximately 2 years, such that subsequent
sensory plasticity is confined primarily to the cortex. However,
recent findings have revealed experience-dependent developmental
plasticity in the mammalian auditory brainstem in an animal model.
It is not known whether the human system demonstrates similar changes
and whether experience with sounds composed of acoustic elements
relevant to speech may alter brainstem response characteristics.
We recorded brainstem responses evoked by both click and speech syllables
in children between the ages of 3 and 12 years. Here, we report a
neural response discrepancy in brainstem encoding of these two sounds,
observed in 3- to 4-year-old children but not in school-age children.
Whereas all children exhibited identical neural activity to a click,
3- to 4-year-old children displayed delayed and less synchronous
onset and sustained neural response activity when elicited by speech
compared with 5- to 12-year-olds. These results suggest that the
human auditory system exhibits developmental plasticity, in both
frequency and time domains, for sounds that are composed of acoustic
elements relevant to speech. The findings are interpreted within
the contexts of stimulus-related differences and experience-dependent
plasticity.
Johnson et al._2008_Developmental plasticity in the human auditory brainstem.pdf:Johnson et al._2008_Developmental plasticity in the human auditory brainstem.pdf:PDF
%0 Journal Article
%1 Johnson2008
%A Johnson, Krista L
%A Nicol, Trent
%A Zecker, Steven G
%A Kraus, Nina
%D 2008
%J Journal of Neuroscience
%K Acoustic Development,Evoked Pathways,Auditory Pathways: Perception,Speech Perception: Plasticity,Neuronal Plasticity: Potentials,Humans,Neuronal Stem,Brain Stem: Stimulation,Acoustic Stimulation: Time,Speech \& development,Brain development,Child,Child growth methods,Aging,Aging: physiology physiology,Auditory,Auditory physiology,Preschool,Reaction
%N 15
%P 4000--7
%R 10.1523/JNEUROSCI.0012-08.2008
%T Developmental plasticity in the human auditory brainstem
%U http://www.ncbi.nlm.nih.gov/pubmed/18400899
%V 28
%X Development of the human auditory brainstem is thought to be primarily
complete by the age of approximately 2 years, such that subsequent
sensory plasticity is confined primarily to the cortex. However,
recent findings have revealed experience-dependent developmental
plasticity in the mammalian auditory brainstem in an animal model.
It is not known whether the human system demonstrates similar changes
and whether experience with sounds composed of acoustic elements
relevant to speech may alter brainstem response characteristics.
We recorded brainstem responses evoked by both click and speech syllables
in children between the ages of 3 and 12 years. Here, we report a
neural response discrepancy in brainstem encoding of these two sounds,
observed in 3- to 4-year-old children but not in school-age children.
Whereas all children exhibited identical neural activity to a click,
3- to 4-year-old children displayed delayed and less synchronous
onset and sustained neural response activity when elicited by speech
compared with 5- to 12-year-olds. These results suggest that the
human auditory system exhibits developmental plasticity, in both
frequency and time domains, for sounds that are composed of acoustic
elements relevant to speech. The findings are interpreted within
the contexts of stimulus-related differences and experience-dependent
plasticity.
@article{Johnson2008,
abstract = {Development of the human auditory brainstem is thought to be primarily
complete by the age of approximately 2 years, such that subsequent
sensory plasticity is confined primarily to the cortex. However,
recent findings have revealed experience-dependent developmental
plasticity in the mammalian auditory brainstem in an animal model.
It is not known whether the human system demonstrates similar changes
and whether experience with sounds composed of acoustic elements
relevant to speech may alter brainstem response characteristics.
We recorded brainstem responses evoked by both click and speech syllables
in children between the ages of 3 and 12 years. Here, we report a
neural response discrepancy in brainstem encoding of these two sounds,
observed in 3- to 4-year-old children but not in school-age children.
Whereas all children exhibited identical neural activity to a click,
3- to 4-year-old children displayed delayed and less synchronous
onset and sustained neural response activity when elicited by speech
compared with 5- to 12-year-olds. These results suggest that the
human auditory system exhibits developmental plasticity, in both
frequency and time domains, for sounds that are composed of acoustic
elements relevant to speech. The findings are interpreted within
the contexts of stimulus-related differences and experience-dependent
plasticity.},
added-at = {2011-03-27T17:20:41.000+0200},
author = {Johnson, Krista L and Nicol, Trent and Zecker, Steven G and Kraus, Nina},
biburl = {https://www.bibsonomy.org/bibtex/2e921486275db0837bf094c478cf49e13/yevb0},
doi = {10.1523/JNEUROSCI.0012-08.2008},
file = {Johnson et al._2008_Developmental plasticity in the human auditory brainstem.pdf:Johnson et al._2008_Developmental plasticity in the human auditory brainstem.pdf:PDF},
interhash = {596276687704f52e8029c722b5483537},
intrahash = {e921486275db0837bf094c478cf49e13},
issn = {1529-2401},
journal = {Journal of Neuroscience},
keywords = {Acoustic Development,Evoked Pathways,Auditory Pathways: Perception,Speech Perception: Plasticity,Neuronal Plasticity: Potentials,Humans,Neuronal Stem,Brain Stem: Stimulation,Acoustic Stimulation: Time,Speech \& development,Brain development,Child,Child growth methods,Aging,Aging: physiology physiology,Auditory,Auditory physiology,Preschool,Reaction},
number = 15,
pages = {4000--7},
pmid = {18400899},
timestamp = {2011-03-27T17:20:55.000+0200},
title = {Developmental plasticity in the human auditory brainstem},
url = {http://www.ncbi.nlm.nih.gov/pubmed/18400899},
volume = 28,
year = 2008
}