%0 Journal Article %1 WOS:000261658800022 %A Jr., Diniz M Sena %A Freire, Paulo T C %A Filho, Josue Mendes %A Melo, Francisco E A %A Pontes, Fenelon M %A Longo, Elson %A Ferreira, Odair P %A Alves, Oswaldo L %C CAIXA POSTAL 26037, 05599-970 SAO PAULO, BRAZIL %D 2008 %I SOC BRASILEIRA QUIMICA %J JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY %K X-ray crystals; diffraction; properties} spectra; thermodynamic vibrational {organic %N 8 %P 1607-1613 %R 10.1590/S0103-50532008000800022 %T Vibrational and Thermal Properties of Crystalline Topiramate %V 19 %X Topiramate, a powerful anticonvulsant drug, was investigated by X-ray diffractometry, FT-Raman, FT-IR, TGA and DTA techniques as well as by DFT calculations. From this study it was possible to tentatively assign most of the normal vibrational modes of the crystal. Thermal analysis from room temperature to 900 degrees C shows that the material does not present any structural phase transition and that the decomposition occurs in a two-step exothermic process.

@article{WOS:000261658800022, abstract = {Topiramate, a powerful anticonvulsant drug, was investigated by X-ray diffractometry, FT-Raman, FT-IR, TGA and DTA techniques as well as by DFT calculations. From this study it was possible to tentatively assign most of the normal vibrational modes of the crystal. Thermal analysis from room temperature to 900 degrees C shows that the material does not present any structural phase transition and that the decomposition occurs in a two-step exothermic process.}, added-at = {2022-05-23T20:00:14.000+0200}, address = {CAIXA POSTAL 26037, 05599-970 SAO PAULO, BRAZIL}, author = {Jr., Diniz M Sena and Freire, Paulo T C and Filho, Josue Mendes and Melo, Francisco E A and Pontes, Fenelon M and Longo, Elson and Ferreira, Odair P and Alves, Oswaldo L}, biburl = {https://www.bibsonomy.org/bibtex/2f897978a5c9cc863c98b9216418e8977/ppgfis_ufc_br}, doi = {10.1590/S0103-50532008000800022}, interhash = {79381906fdd6a020700f987b9914f35e}, intrahash = {f897978a5c9cc863c98b9216418e8977}, issn = {0103-5053}, journal = {JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY}, keywords = {X-ray crystals; diffraction; properties} spectra; thermodynamic vibrational {organic}, number = 8, pages = {1607-1613}, publisher = {SOC BRASILEIRA QUIMICA}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Vibrational and Thermal Properties of Crystalline Topiramate}, tppubtype = {article}, volume = 19, year = 2008 }