%0 Journal Article %1 WOS:000424717800027 %A de Pessoa Nogueira, Luciana Pinho %A de Oliveira, Yara S %A de Fonseca, Jessica C %A Costa, Wendell S %A Raffin, Fernanda N %A Ellena, Javier %A Ayala, Alejandro Pedro %C PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS %D 2018 %I ELSEVIER SCIENCE BV %J JOURNAL OF MOLECULAR STRUCTURE %K Charge Conformational Crystalline Zwitterion; polymorphism; structure; transfer} {Rifampicin; %P 260-266 %R 10.1016/j.molstruc.2017.10.083 %T Crystalline structure of the marketed form of Rifampicin: a case of conformational and charge transfer polymorphism %V 1155 %X Rifampicin is a semi-synthetic drug derived from rifamycin B, and currently integrates the fixed dose combination tablet formulations used in the treatment of tuberculosis. It is also used in the leprosy polychernotherapy and prophylaxis, which are diseases classified as neglected according to the World Health Organization. Rifampicin is a polymorphic drug and its desirable polymorphic form is labeled as II, being the main goal of this study the elucidation of its crystalline structure. Polymorph II is characterized by two molecules with different conformations in the asymmetric unit and the following lattice parameters: a = 14.0760 (10) angstrom

@article{WOS:000424717800027, abstract = {Rifampicin is a semi-synthetic drug derived from rifamycin B, and currently integrates the fixed dose combination tablet formulations used in the treatment of tuberculosis. It is also used in the leprosy polychernotherapy and prophylaxis, which are diseases classified as neglected according to the World Health Organization. Rifampicin is a polymorphic drug and its desirable polymorphic form is labeled as II, being the main goal of this study the elucidation of its crystalline structure. Polymorph II is characterized by two molecules with different conformations in the asymmetric unit and the following lattice parameters: a = 14.0760 (10) angstrom}, added-at = {2022-05-23T20:00:14.000+0200}, address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS}, author = {de Pessoa Nogueira, Luciana Pinho and de Oliveira, Yara S and de Fonseca, Jessica C and Costa, Wendell S and Raffin, Fernanda N and Ellena, Javier and Ayala, Alejandro Pedro}, biburl = {https://www.bibsonomy.org/bibtex/2e7c1262117587e52dd1dc142b34750c7/ppgfis_ufc_br}, doi = {10.1016/j.molstruc.2017.10.083}, interhash = {3d323cc3498eed94bcbd5f240d032feb}, intrahash = {e7c1262117587e52dd1dc142b34750c7}, issn = {0022-2860}, journal = {JOURNAL OF MOLECULAR STRUCTURE}, keywords = {Charge Conformational Crystalline Zwitterion; polymorphism; structure; transfer} {Rifampicin;}, pages = {260-266}, publisher = {ELSEVIER SCIENCE BV}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Crystalline structure of the marketed form of Rifampicin: a case of conformational and charge transfer polymorphism}, tppubtype = {article}, volume = 1155, year = 2018 }