Article,

Enzyme modulators as tools for the development of homogeneous enzyme immunoassays.

, and .
FEBS Lett, 116 (2): 285--288 (July 1980)
DOI: 10.1016/0014-5793(80)80664-8

Abstract

Here we describe a different approach to homogeneous enzyme immunoassays, one that employs an enzyme modulator (Emmia). An enzyme modulator may be an antibody, inhibitor or receptor to the marker (i.e., indicator) enzyme. The modulator must be covalently linked to a ligand that is similar to the analyte so that the amount of modulator free to regulate the available indicator enzyme is dependent upon the amount of analyte to be determined.

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