%0 Journal Article %1 sonu_gangwar_2023_7939913 %A Gangwar, Sonu %A Semwal, Nidhi %A Joshi, Deepika %A Singh, Bhavana %D 2023 %J World Journal of Biology Pharmacy and Health Sciences %K Diclofenac sodium %N 1 %P 103-110 %R 10.30574/wjbphs.2023.13.1.0246 %T Formulation and evaluation of biodegradable floating drug delivery for solubility enhancement of diclofenac sodium %U https://wjbphs.com/content/formulation-and-evaluation-biodegradable-floating-drug-delivery-solubility-enhancement %V 13 %X This learning's objective is to determine and investigate how pharmaceutical restrictions affect the characteristics of gastric floating tablets using diclofenac sodium (DICL) as a model for the solubility enhancement, sodium-bicarbonate (NaHCO3) or calcium-carbonate (CaCO3). Hydroxypropyl Methylcellulose (HPMC) as swelling polymer K100M or K15M is a gas-forming substance. BY direct-compression manufacturing is used to create floating DICL tablets. The tablet characteristics, swelling index, and in vitro resistance of compressed tablets were assessed. Under non-reducing circumstances, in vitro release was identified. Molecular interactions have been investigated using Fourier transform infrared spectroscopy and differential scanning calorimetry.

@article{sonu_gangwar_2023_7939913, abstract = {This learning's objective is to determine and investigate how pharmaceutical restrictions affect the characteristics of gastric floating tablets using diclofenac sodium (DICL) as a model for the solubility enhancement, sodium-bicarbonate (NaHCO3) or calcium-carbonate (CaCO3). Hydroxypropyl Methylcellulose (HPMC) as swelling polymer K100M or K15M is a gas-forming substance. BY direct-compression manufacturing is used to create floating DICL tablets. The tablet characteristics, swelling index, and in vitro resistance of compressed tablets were assessed. Under non-reducing circumstances, in vitro release was identified. Molecular interactions have been investigated using Fourier transform infrared spectroscopy and differential scanning calorimetry.}, added-at = {2023-07-17T03:13:06.000+0200}, author = {Gangwar, Sonu and Semwal, Nidhi and Joshi, Deepika and Singh, Bhavana}, biburl = {https://www.bibsonomy.org/bibtex/250e0ac63b45129086935af85f8d4522c/wjbphsjournal}, doi = {10.30574/wjbphs.2023.13.1.0246}, interhash = {40ae82457e5df53e40756757148b5fdb}, intrahash = {50e0ac63b45129086935af85f8d4522c}, issn = {2582-5542}, journal = {{World Journal of Biology Pharmacy and Health Sciences}}, keywords = {Diclofenac sodium}, month = jan, number = 1, pages = {103-110}, timestamp = {2023-07-17T03:13:06.000+0200}, title = {Formulation and evaluation of biodegradable floating drug delivery for solubility enhancement of diclofenac sodium}, url = {https://wjbphs.com/content/formulation-and-evaluation-biodegradable-floating-drug-delivery-solubility-enhancement}, volume = 13, year = 2023 }