%0 Journal Article %1 riva2018improved %A Riva, Antonella %A Ronchi, Massimo %A Petrangolini, Giovanna %A Bosisio, Stefani %A Allegrini, Pietro %D 2018 %J European Journal of Drug Metabolism and Pharmacokinetics %K Quercetin absorption %P 169-177 %R 10.1007%2Fs13318-018-0517-3 %T Improved Oral Absorption of Quercetin from Quercetin Phytosome®, a New Delivery System Based on Food Grade Lecithin %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418071/ %X The importance of quercetin and flavonoids in the diet and as food supplements is well known, and literature studies support their potential use to treat several human diseases. Many beneficial properties have been described for quercetin, so much effort has been directed into overcoming the major drawbacks of this natural compound—its poor solubility and low oral absorption. The aims of this study were to compare a new food-grade lecithin-based formulation of quercetin, Quercetin Phytosome®, to unformulated quercetin in terms of solubility in simulated gastrointestinal fluids and oral absorption in a randomized crossover pharmacokinetic study of healthy volunteers.

@article{riva2018improved, abstract = {The importance of quercetin and flavonoids in the diet and as food supplements is well known, and literature studies support their potential use to treat several human diseases. Many beneficial properties have been described for quercetin, so much effort has been directed into overcoming the major drawbacks of this natural compound—its poor solubility and low oral absorption. The aims of this study were to compare a new food-grade lecithin-based formulation of quercetin, Quercetin Phytosome®, to unformulated quercetin in terms of solubility in simulated gastrointestinal fluids and oral absorption in a randomized crossover pharmacokinetic study of healthy volunteers.}, added-at = {2021-07-08T12:43:30.000+0200}, author = {Riva, Antonella and Ronchi, Massimo and Petrangolini, Giovanna and Bosisio, Stefani and Allegrini, Pietro}, biburl = {https://www.bibsonomy.org/bibtex/2ff015bb42f4ef03ef78a63c0500fd9b3/bellao}, doi = {10.1007%2Fs13318-018-0517-3}, interhash = {41d614d6a6358c9798bab54bd28a22e0}, intrahash = {ff015bb42f4ef03ef78a63c0500fd9b3}, journal = {European Journal of Drug Metabolism and Pharmacokinetics}, keywords = {Quercetin absorption}, month = oct, pages = {169-177}, timestamp = {2022-04-24T20:01:55.000+0200}, title = {Improved Oral Absorption of Quercetin from Quercetin Phytosome®, a New Delivery System Based on Food Grade Lecithin}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418071/}, year = 2018 }