%0 Journal Article %1 raghavan2014genetic %A Raghavan, M %A DeGiorgio, M %A Albrechtsen, A %A Moltke, I %A Skoglund, P %A Korneliussen, T S %A Gronnow, B %A Appelt, M %A Gullov, H C %A Friesen, T M %A Fitzhugh, W %A Malmström, H %A Rasmussen, S %A Olsen, J %A Melchior, L %A Fuller, B T %A Fahrni, S M %A Stafford, T %A Grimes, V %A Renouf, M A %A Cybulski, J %A Lynnerup, N %A Lahr, M M %A Britton, K %A Knecht, R %A Arneborg, J %A Metspalu, M %A Cornejo, O E %A Malaspinas, A S %A Wang, Y %A Rasmussen, M %A Raghavan, V %A Hansen, T V %A Khusnutdinova, E %A Pierre, T %A Dneprovsky, K %A Andreasen, C %A Lange, H %A Hayes, M G %A Coltrain, J %A Spitsyn, V A %A Götherström, A %A Orlando, L %A Kivisild, T %A Villems, R %A Crawford, M H %A Nielsen, F C %A Dissing, J %A Heinemeier, J %A Meldgaard, M %A Bustamante, C %A O'Rourke, D H %A Jakobsson, M %A Gilbert, M T %A Nielsen, R %A Willerslev, E %D 2014 %J Science %K ancient_DNA human_genome migration time_series %N 6200 %P 1255832-1255832 %R 10.1126/science.1255832 %T The genetic prehistory of the New World Arctic %U http://www.ncbi.nlm.nih.gov/pubmed/25170159 %V 345 %X The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (\~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.

@article{raghavan2014genetic, abstract = {The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (\~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.}, added-at = {2014-09-01T02:34:19.000+0200}, author = {Raghavan, M and DeGiorgio, M and Albrechtsen, A and Moltke, I and Skoglund, P and Korneliussen, T S and Gronnow, B and Appelt, M and Gullov, H C and Friesen, T M and Fitzhugh, W and Malmstr{\"o}m, H and Rasmussen, S and Olsen, J and Melchior, L and Fuller, B T and Fahrni, S M and Stafford, T and Grimes, V and Renouf, M A and Cybulski, J and Lynnerup, N and Lahr, M M and Britton, K and Knecht, R and Arneborg, J and Metspalu, M and Cornejo, O E and Malaspinas, A S and Wang, Y and Rasmussen, M and Raghavan, V and Hansen, T V and Khusnutdinova, E and Pierre, T and Dneprovsky, K and Andreasen, C and Lange, H and Hayes, M G and Coltrain, J and Spitsyn, V A and G{\"o}therstr{\"o}m, A and Orlando, L and Kivisild, T and Villems, R and Crawford, M H and Nielsen, F C and Dissing, J and Heinemeier, J and Meldgaard, M and Bustamante, C and O'Rourke, D H and Jakobsson, M and Gilbert, M T and Nielsen, R and Willerslev, E}, biburl = {https://www.bibsonomy.org/bibtex/25703664b3c57d27df001f0e7a86951a7/peter.ralph}, doi = {10.1126/science.1255832}, interhash = {566f1fe1a912bdf959e028cf3d3467dc}, intrahash = {5703664b3c57d27df001f0e7a86951a7}, journal = {Science}, keywords = {ancient_DNA human_genome migration time_series}, month = aug, number = 6200, pages = {1255832-1255832}, pmid = {25170159}, timestamp = {2014-09-01T02:34:19.000+0200}, title = {The genetic prehistory of the {New} {World} {Arctic}}, url = {http://www.ncbi.nlm.nih.gov/pubmed/25170159}, volume = 345, year = 2014 }