%0 Journal Article %1 manzur_natural_2010 %A Manzur, A. %A Dominguez, M.A. %A de Gopegui, E. Ruiz %A Mariscal, D. %A Gavalda, L. %A Segura, F. %A Perez, J.L. %A Pujol, M. %D 2010 %J Journal of Hospital Infection %K Epidemiology, Geriatrics, Long Meticillin-resistant Staphylococcus aureus care, term %N 3 %P 215--219 %R 10.1016/j.jhin.2010.05.022 %T Natural history of meticillin-resistant Staphylococcus aureus colonisation among residents in community long term care facilities in Spain %U http://www.sciencedirect.com/science/article/B6WJP-50RFMN0-3/2/40df0ecac708dfea35202bb79aad7a52 %V 76 %X Summary The spread of meticillin-resistant Staphylococcus aureus (MRSA) is a major problem for both acute care hospitals and among residents in long term care facilities (LTCFs). We performed a cohort study to assess the natural history of MRSA colonisation in LTCF residents. Two cohorts of residents (231 MRSA carriers and 196 non-carriers) were followed up for an 18 month period, with cultures of nasal and decubitus ulcers performed every six months. In the MRSA carrier cohort, 110 (47.8\%) residents had persistent MRSA colonisation for six months or longer, 44 (19.0\%) had transient colonisation and nine (3.9\%) were intermittently colonised. No risk factors for persistent MRSA colonisation could be determined. The annual incidence of MRSA acquisition was around 20\% 95\% confidence interval (CI): 14.3-25.5. Antibiotic treatment was independently associated with MRSA acquisition (odds ratio: 2.27; 95\% CI: 1.05-4.88; P = 0.03). Just two clones were distinguishable by pulsed-field gel electrophoresis and multilocus sequence typing: CC5-MRSA IV, which is widely disseminated in Spanish hospitals, and ST22-MRSA IV. This study adds to the knowledge of the epidemiology of MRSA in community LTCFs, which are important components of long term care in Spain.

@article{manzur_natural_2010, abstract = {Summary The spread of meticillin-resistant Staphylococcus aureus {(MRSA)} is a major problem for both acute care hospitals and among residents in long term care facilities {(LTCFs).} We performed a cohort study to assess the natural history of {MRSA} colonisation in {LTCF} residents. Two cohorts of residents (231 {MRSA} carriers and 196 non-carriers) were followed up for an 18 month period, with cultures of nasal and decubitus ulcers performed every six months. In the {MRSA} carrier cohort, 110 (47.8\%) residents had persistent {MRSA} colonisation for six months or longer, 44 (19.0\%) had transient colonisation and nine (3.9\%) were intermittently colonised. No risk factors for persistent {MRSA} colonisation could be determined. The annual incidence of {MRSA} acquisition was around 20\% [95\% confidence interval {(CI):} 14.3-25.5]. Antibiotic treatment was independently associated with {MRSA} acquisition (odds ratio: 2.27; 95\% {CI:} 1.05-4.88; P = 0.03). Just two clones were distinguishable by pulsed-field gel electrophoresis and multilocus sequence typing: {CC5-MRSA} {IV,} which is widely disseminated in Spanish hospitals, and {ST22-MRSA} {IV.} This study adds to the knowledge of the epidemiology of {MRSA} in community {LTCFs,} which are important components of long term care in Spain.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Manzur, A. and Dominguez, {M.A.} and de Gopegui, E. Ruiz and Mariscal, D. and Gavalda, L. and Segura, F. and Perez, {J.L.} and Pujol, M.}, biburl = {https://www.bibsonomy.org/bibtex/2aee01d52a4c4f3a8fd59bf0434856fa1/jelias}, doi = {10.1016/j.jhin.2010.05.022}, interhash = {5a39fcf649c5ae17e244fd65d1150f41}, intrahash = {aee01d52a4c4f3a8fd59bf0434856fa1}, issn = {0195-6701}, journal = {Journal of Hospital Infection}, keywords = {Epidemiology, Geriatrics, Long Meticillin-resistant Staphylococcus aureus care, term}, month = nov, number = 3, pages = {215--219}, timestamp = {2011-03-11T10:05:50.000+0100}, title = {Natural history of meticillin-resistant Staphylococcus aureus colonisation among residents in community long term care facilities in Spain}, url = {http://www.sciencedirect.com/science/article/B6WJP-50RFMN0-3/2/40df0ecac708dfea35202bb79aad7a52}, volume = 76, year = 2010 }