%0 Journal Article %1 noauthororeditor %A Mehboob, Riffat %A Munir, Muhammad %A Azeem, Ahmed %A Naeem, Samina %A Ahmad, FridoonJawad %D 2015 %J International Journal of Advances in Chemistry (IJAC) %K Dengue Lahore bleeding count platelet tendency %N 1 %P 31-36 %R 10.5121/ijac.2015.1103 %T LOW PLATELET COUNT ASSOCIATED WITH DENGUE HEMORRHAGIC FEVER %U http://airccse.com/ijac/papers/1115ijac03.pdf %V 1 %X Dengue is an infectious mosquito borne disease of tropical regions. There is a drastic change in the demographic characteristics of dengue fever in Pakistan over the past years. Many small studies have been done previously all over the country but the data reported so far regarding demographic, biochemical and hematological parameters of dengue infection is insufficient. This study was undertaken to establish a possible association of decrease in platelet count with bleeding tendency in dengue patients. It is an observational cross-sectional study conducted on 50 sero positive cases during the early days of dengue virus infection (1-7 days) confirmed by Real time PCR (CDC Atlanta) in a tertiary care hospital in Lahore. Patients of both sexes and all age groups were included. The study was approved from ethical committee of King Edward Medical University. 3-5 ml of venous blood was taken from the patients during first 7 days of infection for CBC analysis. Consent was taken from patients or guardian in case of children and proforma was also filled after interviewing the patient. This article assesses the association of severity of disease with age, gender, platelet count and bleeding tendencies in dengue patients. More dengue patients had declined platelet counts (<50,000/µl). Dengue infection was more in age group 16-30 years but hemorrhagic signs were more in females and in older patients. Out of 50 patients 22 were males and 28 were females. Platelet count of dengue patients is mostly less than 150,000 per micro liter while normal range is 150,000 to 400,000 per micro liter. Platelet count of female patients is lower as compared to males, DHF is more in females and Hb has no correlation with bleeding tendency while an association has been found between low platelet count and increased bleeding tendency among the infected patients. Median age of dengue patients has decreased and younger patients especially males may be more susceptible.

@article{noauthororeditor, abstract = {Dengue is an infectious mosquito borne disease of tropical regions. There is a drastic change in the demographic characteristics of dengue fever in Pakistan over the past years. Many small studies have been done previously all over the country but the data reported so far regarding demographic, biochemical and hematological parameters of dengue infection is insufficient. This study was undertaken to establish a possible association of decrease in platelet count with bleeding tendency in dengue patients. It is an observational cross-sectional study conducted on 50 sero positive cases during the early days of dengue virus infection (1-7 days) confirmed by Real time PCR (CDC Atlanta) in a tertiary care hospital in Lahore. Patients of both sexes and all age groups were included. The study was approved from ethical committee of King Edward Medical University. 3-5 ml of venous blood was taken from the patients during first 7 days of infection for CBC analysis. Consent was taken from patients or guardian in case of children and proforma was also filled after interviewing the patient. This article assesses the association of severity of disease with age, gender, platelet count and bleeding tendencies in dengue patients. More dengue patients had declined platelet counts (<50,000/µl). Dengue infection was more in age group 16-30 years but hemorrhagic signs were more in females and in older patients. Out of 50 patients 22 were males and 28 were females. Platelet count of dengue patients is mostly less than 150,000 per micro liter while normal range is 150,000 to 400,000 per micro liter. Platelet count of female patients is lower as compared to males, DHF is more in females and Hb has no correlation with bleeding tendency while an association has been found between low platelet count and increased bleeding tendency among the infected patients. Median age of dengue patients has decreased and younger patients especially males may be more susceptible. }, added-at = {2018-05-24T08:56:19.000+0200}, author = {Mehboob, Riffat and Munir, Muhammad and Azeem, Ahmed and Naeem, Samina and Ahmad, FridoonJawad}, biburl = {https://www.bibsonomy.org/bibtex/2e2e82e58779ca35a1b47ca8678bbb479/ijac}, doi = {10.5121/ijac.2015.1103}, interhash = {5be675402956664dc90970121d50f7b0}, intrahash = {e2e82e58779ca35a1b47ca8678bbb479}, issn = {2455-7862}, journal = { International Journal of Advances in Chemistry (IJAC) }, keywords = {Dengue Lahore bleeding count platelet tendency}, language = {English}, month = {2015}, number = 1, pages = {31-36}, timestamp = {2018-05-24T08:56:19.000+0200}, title = {LOW PLATELET COUNT ASSOCIATED WITH DENGUE HEMORRHAGIC FEVER}, url = {http://airccse.com/ijac/papers/1115ijac03.pdf}, volume = 1, year = 2015 }