%0 Journal Article %1 valenza_analysis_2006 %A Valenza, Giuseppe %A Burgemeister, Stefan %A Girschick, Hermann %A Schoen, Christoph %A Veihelmann, Simone %A Moter, Annette %A Haban, Vesna %A Vogel, Ulrich %A Schlagenhauf, Ulrich %D 2006 %J International Journal of Medical Microbiology: IJMM %K Acid Adolescent, Adult, Analysis, Bacteria, Bacterial, Child, Cohort Data, Dental Genes, Homology, Humans, Hybridization, Hypophosphatasia, Index, Male, Molecular Nucleic Periodontal Periodontitis, Plaque, Pocket, Ribosomal, Sequence Studies, ag_horn {16S,} {DNA,} {RNA,} {rRNA,} %N 7 %P 493--500 %R 10.1016/j.ijmm.2006.05.002 %T Analysis of the periodontal microbiota in childhood-type hypophosphatasia %U http://www.ncbi.nlm.nih.gov/pubmed/16875876 %V 296 %X Seven patients with childhood-type hypophosphatasia and healthy control subjects were analysed for microbiological and clinical evidence of periodontitis. The bacterial composition of the subgingival plaque was analysed by 16S rRNA gene cloning and sequencing, DNA-DNA hybridisation with specific probes, and specific PCR. With the exception of the genus Veillonella and the species Eikenella corrodens, no differences between the cohorts in the composition of bacterial orders, families, genera, and species were observed. Accordingly, patients showed only slightly more bleeding on probing (BOP), and slightly higher periodontal probing depth (PPD) values than controls. Although this pilot study did not have the power to assess the prevalence of periodontitis in HP, we suggest that most paediatric patients suffering from HP harbour a subgingival microbiota, which is comparable to that of the healthy population.

@article{valenza_analysis_2006, abstract = {Seven patients with childhood-type hypophosphatasia and healthy control subjects were analysed for microbiological and clinical evidence of periodontitis. The bacterial composition of the subgingival plaque was analysed by {16S} {rRNA} gene cloning and sequencing, {DNA-DNA} hybridisation with specific probes, and specific {PCR.} With the exception of the genus Veillonella and the species Eikenella corrodens, no differences between the cohorts in the composition of bacterial orders, families, genera, and species were observed. Accordingly, patients showed only slightly more bleeding on probing {(BOP),} and slightly higher periodontal probing depth {(PPD)} values than controls. Although this pilot study did not have the power to assess the prevalence of periodontitis in {HP,} we suggest that most paediatric patients suffering from {HP} harbour a subgingival microbiota, which is comparable to that of the healthy population.}, added-at = {2011-04-07T15:44:20.000+0200}, author = {Valenza, Giuseppe and Burgemeister, Stefan and Girschick, Hermann and Schoen, Christoph and Veihelmann, Simone and Moter, Annette and Haban, Vesna and Vogel, Ulrich and Schlagenhauf, Ulrich}, biburl = {https://www.bibsonomy.org/bibtex/24551520ff75ab3038a66a136d57256f9/hymi}, doi = {10.1016/j.ijmm.2006.05.002}, interhash = {63096b29972135263588b82dc5f01657}, intrahash = {4551520ff75ab3038a66a136d57256f9}, issn = {1438-4221}, journal = {International Journal of Medical Microbiology: {IJMM}}, keywords = {Acid Adolescent, Adult, Analysis, Bacteria, Bacterial, Child, Cohort Data, Dental Genes, Homology, Humans, Hybridization, Hypophosphatasia, Index, Male, Molecular Nucleic Periodontal Periodontitis, Plaque, Pocket, Ribosomal, Sequence Studies, ag_horn {16S,} {DNA,} {RNA,} {rRNA,}}, month = nov, note = {{PMID:} 16875876}, number = 7, pages = {493--500}, timestamp = {2011-04-07T16:38:32.000+0200}, title = {Analysis of the periodontal microbiota in childhood-type hypophosphatasia}, url = {http://www.ncbi.nlm.nih.gov/pubmed/16875876}, volume = 296, year = 2006 }