%0 Journal Article %1 Teli2006 %A Teli, Marco G A %A Cinnella, Pasquale %A Vincitorio, Fiammetta %A Lovi, Alessio %A Grava, Giuseppe %A Brayda-Bruno, Marco %D 2006 %J Spine %K Adolescent; Adult; Cerebral Palsy; Child; Cohort Studies; Female; Follow-Up Humans; Incidence; Infection; Internal Fixators; Male; Patient Satisfaction; Pseudarthrosis; Quadriplegia; Quality of Life; Questionnaires; Retrospective Scoliosis; Spinal Fusion; Treatment Outcome %N 14 %P E441--E447 %R 10.1097/01.brs.0000221986.07992.fb %T Spinal fusion with Cotrel-Dubousset instrumentation for neuropathic scoliosis in patients with cerebral palsy. %U http://dx.doi.org/10.1097/01.brs.0000221986.07992.fb %V 31 %X STUDY DESIGN: Retrospective. OBJECTIVE: To report on the treatment of patients with cerebral palsy and neuropathic scoliosis with third-generation instrumented spinal fusion by Cotrel-Dubousset instrumentation. SUMMARY OF BACKGROUND DATA: Second-generation instrumented spinal fusion is considered the standard for progressive neuropathic scoliosis in cerebral palsy, despite high complication rates. Evidence is needed to evaluate the increasing use of third-generation instrumented spinal fusion in similar patients. METHODS: Patients with cerebral palsy and spinal deformity treated consecutively by 1 surgeon with Cotrel-Dubousset instrumentation and minimum 2-year follow-up were reviewed. An outcome questionnaire was administered at final follow-up. RESULTS: A total of 60 patients were included. Mean age was 15 years at surgery. Mean follow-up was 79 months. There were 26 anteroposterior and 34 posterior-only procedures. Correction of coronal deformity and pelvic obliquity averaged 60\% and 40\%, respectively. Major complications affected 13.5\% of patients, and included implant loosening, deep infection, and pseudarthrosis. Minor complications affected 10\% of patients. Outcome questionnaires showed marked improvements in the areas of satisfaction, function, and quality of life after surgery. CONCLUSIONS: Segmental, third-generation instrumented spinal fusion provides lasting correction of spinal deformity and improved quality of life in patients with cerebral palsy and neuropathic scoliosis, with a lower pseudarthrosis rate compared to reports on second-generation instrumented spinal fusion.

@article{Teli2006, abstract = {STUDY DESIGN: Retrospective. OBJECTIVE: To report on the treatment of patients with cerebral palsy and neuropathic scoliosis with third-generation instrumented spinal fusion by Cotrel-Dubousset instrumentation. SUMMARY OF BACKGROUND DATA: Second-generation instrumented spinal fusion is considered the standard for progressive neuropathic scoliosis in cerebral palsy, despite high complication rates. Evidence is needed to evaluate the increasing use of third-generation instrumented spinal fusion in similar patients. METHODS: Patients with cerebral palsy and spinal deformity treated consecutively by 1 surgeon with Cotrel-Dubousset instrumentation and minimum 2-year follow-up were reviewed. An outcome questionnaire was administered at final follow-up. RESULTS: A total of 60 patients were included. Mean age was 15 years at surgery. Mean follow-up was 79 months. There were 26 anteroposterior and 34 posterior-only procedures. Correction of coronal deformity and pelvic obliquity averaged 60\% and 40\%, respectively. Major complications affected 13.5\% of patients, and included implant loosening, deep infection, and pseudarthrosis. Minor complications affected 10\% of patients. Outcome questionnaires showed marked improvements in the areas of satisfaction, function, and quality of life after surgery. CONCLUSIONS: Segmental, third-generation instrumented spinal fusion provides lasting correction of spinal deformity and improved quality of life in patients with cerebral palsy and neuropathic scoliosis, with a lower pseudarthrosis rate compared to reports on second-generation instrumented spinal fusion.}, added-at = {2014-07-19T21:42:45.000+0200}, author = {Teli, Marco G A and Cinnella, Pasquale and Vincitorio, Fiammetta and Lovi, Alessio and Grava, Giuseppe and Brayda-Bruno, Marco}, biburl = {https://www.bibsonomy.org/bibtex/2da9ebf8379600aa9199be086561a8f5e/ar0berts}, doi = {10.1097/01.brs.0000221986.07992.fb}, groups = {public}, interhash = {6e2d4a540b089bbe208f80b1fc605d0d}, intrahash = {da9ebf8379600aa9199be086561a8f5e}, journal = {Spine}, keywords = {Adolescent; Adult; Cerebral Palsy; Child; Cohort Studies; Female; Follow-Up Humans; Incidence; Infection; Internal Fixators; Male; Patient Satisfaction; Pseudarthrosis; Quadriplegia; Quality of Life; Questionnaires; Retrospective Scoliosis; Spinal Fusion; Treatment Outcome}, month = Jun, number = 14, pages = {E441--E447}, pii = {00007632-200606150-00030}, pmid = {16778673}, timestamp = {2014-07-19T21:48:05.000+0200}, title = {Spinal fusion with Cotrel-Dubousset instrumentation for neuropathic scoliosis in patients with cerebral palsy.}, url = {http://dx.doi.org/10.1097/01.brs.0000221986.07992.fb}, username = {ar0berts}, volume = 31, year = 2006 }